Buttarelli L, Capocasale E, Marcato C, Mazzoni M P, Iaria M, Rossi C
Department of Diagnostic and Interventional Radiology, University of Parma, Parma Hospital, Parma, Italy.
Transplant Proc. 2011 Dec;43(10):4044-7. doi: 10.1016/j.transproceed.2011.08.099.
Vascular complications remain a major cause of graft loss after pancreatic transplantation. They include vascular thrombosis, pseudoaneurysm, and arteriovenous fistula (AVF). We report a case of an AVF that appeared 3 months after a simultaneous pancreas-kidney transplantation (SPKT). Doppler ultrasonography followed by magnetic resonance angiography and later angiography provided a definitive diagnosis of a mesenteric AVF. An endovascular approach is becoming the treatment of choice owing to the high risk of graft loss associated with open surgical correction. Microcoils alone, or in conjunction with detachable balloons, are frequently used; still, a new generation of vascular plugs seem to offer a therapeutic option for AVF closure, because it is a "1 shot" procedure that avoids the risk of accidental coil migration. A new-generation Amplatzer Vascular Plug 4 was deployed over the distal arterial branch of the superior mesenteric artery stump, leading to complete exclusion of the AVF and restoring normal vascular flow.
血管并发症仍然是胰腺移植后移植物丢失的主要原因。这些并发症包括血管血栓形成、假性动脉瘤和动静脉瘘(AVF)。我们报告一例在同期胰肾联合移植(SPKT)后3个月出现的AVF病例。通过多普勒超声检查,随后进行磁共振血管造影及血管造影,最终确诊为肠系膜动静脉瘘。由于开放手术矫正与移植物丢失的高风险相关,血管内介入方法正成为首选治疗方式。单独使用微线圈或与可脱卸球囊联合使用较为常见;不过,新一代血管封堵器似乎为AVF封堵提供了一种治疗选择,因为它是一种“一次性”操作,可避免线圈意外移位的风险。新一代Amplatzer血管封堵器4型被放置在上肠系膜动脉残端的远端动脉分支上,从而完全封闭了AVF并恢复了正常的血流。