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实体器官移植受者中供体来源的粗球孢子菌血症

Donor-derived Coccidioides immitis fungemia in solid organ transplant recipients.

作者信息

Blodget E, Geiseler P Jan, Larsen R A, Stapfer M, Qazi Y, Petrovic L M

机构信息

Division of Infectious Diseases, Department of Medicine, University of Southern California Keck School of Medicine, Los Angeles, California 90033, USA.

出版信息

Transpl Infect Dis. 2012 Jun;14(3):305-10. doi: 10.1111/j.1399-3062.2011.00698.x. Epub 2011 Dec 18.

Abstract

We report disseminated coccidioidomycosis in 3 transplant recipients from a donor in an endemic area found to have unrecognized meningeal coccidioidomycosis. All 3 transplant recipients presented within 3 weeks of receipt of their organ. Only 1 organ recipient survived the acute presentation of coccidioidomycosis. Serologic testing for Coccidioides immitis infection should be considered for organ donors residing in endemic areas.

摘要

我们报告了3名移植受者发生播散性球孢子菌病,供体来自流行地区,被发现患有未被识别的脑膜球孢子菌病。所有3名移植受者在接受器官后的3周内发病。只有1名器官受者在球孢子菌病急性期存活下来。对于居住在流行地区的器官供体,应考虑进行针对粗球孢子菌感染的血清学检测。

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