Suppr超能文献

重度颈动脉和冠状动脉疾病患者分期颈动脉内膜切除术和冠状动脉搭桥术的结果。

Results of staged carotid endarterectomy and coronary artery bypass graft in patients with severe carotid and coronary disease.

作者信息

Santos Angelo, Washington Christopher, Rahbar Rodeen, Benckart Daniel, Muluk Satish

机构信息

Allegheny General Hospital, The Gerald McGinnis Cardiovascular Institute, Pittsburgh, PA 15212, USA.

出版信息

Ann Vasc Surg. 2012 Jan;26(1):102-6. doi: 10.1016/j.avsg.2011.10.002.

Abstract

BACKGROUND

To evaluate our experience with staged carotid endarterectomy (CEA) followed by coronary artery bypass grafting (CABG) within the perioperative period for patients with severe carotid and coronary artery disease.

METHODS

From 1998 to August of 2010, 40 patients who were referred for isolated coronary surgery were found to have significant carotid disease. All patients underwent CEA followed by subsequent CABG within 30 days of the CEA. Severe carotid stenosis was defined as >70%.

RESULTS

Average patient age was 65.5 ± 10.6 years and 32 (80%) were male. Severe carotid stenosis was unilateral in 37 of the patients, bilateral in 3, and asymptomatic in 37. Patients underwent CEA with either patch angioplasty or eversion technique. General anesthesia with selective shunting was used in all cases. There were zero deaths, zero strokes, and one myocardial infarction (MI) (2.5%) immediately after CEA. After CEA, CABG was performed within 30 days. The average interval between procedures was 6.87 days. There were two (5.0%) deaths, one from MI and the other from multisystem organ failure. There were two strokes (5.0%), with one having permanent effects. The perioperative mortality, stroke, and MI rates after both operations were 5.0%, 5.0%, and 5.0%, respectively.

CONCLUSIONS

Staging of CEA followed by CABG in the immediate perioperative period may be an acceptable approach to patients with severe carotid and coronary disease. Despite the presence of known severe coronary disease, the performance of CEA under general anesthesia as the initial procedure was well tolerated. We propose that this strategy may be a possible option for patients who present with severe disease in both coronary and carotid distributions. The results of our study, though based on a limited cohort, suggest that this approach of staged CEA-CABG within the perioperative period <30 days is reasonable.

摘要

背景

评估我们在围手术期对患有严重颈动脉和冠状动脉疾病的患者先进行分期颈动脉内膜切除术(CEA),随后进行冠状动脉旁路移植术(CABG)的经验。

方法

从1998年至2010年8月,40例因单纯冠状动脉手术前来就诊的患者被发现患有严重颈动脉疾病。所有患者均接受了CEA,并且在CEA术后30天内接受了后续的CABG。严重颈动脉狭窄定义为>70%。

结果

患者平均年龄为65.5±10.6岁,32例(80%)为男性。37例患者的严重颈动脉狭窄为单侧,3例为双侧,37例无症状。患者接受了使用补片血管成形术或外翻技术的CEA。所有病例均采用全身麻醉并选择性分流。CEA术后即刻死亡0例,卒中0例,心肌梗死(MI)1例(2.5%)。CEA术后,在30天内进行了CABG。两次手术之间的平均间隔时间为6.87天。有2例(5.0%)死亡,1例死于MI,另1例死于多系统器官衰竭。有2例卒中(5.0%),其中1例有永久性影响。两次手术的围手术期死亡率、卒中和MI发生率分别为5.0%、5.0%和5.0%。

结论

在围手术期即刻先进行CEA再进行CABG,对于患有严重颈动脉和冠状动脉疾病的患者可能是一种可接受的方法。尽管存在已知的严重冠状动脉疾病,但作为初始手术在全身麻醉下进行CEA耐受性良好。我们提出,对于在冠状动脉和颈动脉分布区均患有严重疾病的患者,这种策略可能是一种可行的选择。我们的研究结果虽然基于有限的队列,但表明在<30天的围手术期内进行分期CEA-CABG的这种方法是合理的。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验