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Genomically humanized mice: technologies and promises.
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Artificial chromosome transgenesis in pigmentary research.
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Creation of non-human primate neurogenetic disease models by gene targeting and nuclear transfer.
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Transchromosomic technology for genomically humanized animals.
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Mouse embryonic stem cells with a multi-integrase mouse artificial chromosome for transchromosomic mouse generation.
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A Simple Guide for Generating BAC Transgenic Animals for Retinal Research.
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Integrase-Mediated Targeted Transgenics Through Pronuclear Microinjection.
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Site-specific transgenesis by Cre-mediated recombination in Drosophila.
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The ons and offs of inducible transgenic technology: a review.
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Remote control of gene expression.
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Organoids in Genetic Disorders: from Disease Modeling to Translational Applications.
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Gene therapy shines light on congenital stationary night blindness for future cures.
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A review of the complex interplay between chemoresistance and lncRNAs in lung cancer.
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Efficient and safe in vivo treatment of primary hyperoxaluria type 1 via LNP-CRISPR-Cas9-mediated glycolate oxidase disruption.
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A humanized knock-in mouse recapitulates a deep-intronic splice-activating variant.
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Construction and characterization of a humanized rat model with its application in evaluating the uptake of different statins.
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Roles of long noncoding RNA in triple-negative breast cancer.
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Modeling the Tumor Microenvironment and Cancer Immunotherapy in Next-Generation Humanized Mice.
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本文引用的文献

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Intermolecular transmission of superoxide dismutase 1 misfolding in living cells.
Proc Natl Acad Sci U S A. 2011 Sep 27;108(39):16398-403. doi: 10.1073/pnas.1102645108. Epub 2011 Sep 19.
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Efficient differentiation and function of human macrophages in humanized CSF-1 mice.
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Streamlined platform for short hairpin RNA interference and transgenesis in cultured mammalian cells.
Proc Natl Acad Sci U S A. 2011 Aug 2;108(31):12799-804. doi: 10.1073/pnas.1103532108. Epub 2011 Jul 18.
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Human artificial chromosomes for gene delivery and the development of animal models.
Mol Ther. 2011 Sep;19(9):1591-601. doi: 10.1038/mt.2011.136. Epub 2011 Jul 12.
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In vivo genome editing restores haemostasis in a mouse model of haemophilia.
Nature. 2011 Jun 26;475(7355):217-21. doi: 10.1038/nature10177.
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A genetically humanized mouse model for hepatitis C virus infection.
Nature. 2011 Jun 8;474(7350):208-11. doi: 10.1038/nature10168.
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Structural and functional differences in the long non-coding RNA hotair in mouse and human.
PLoS Genet. 2011 May;7(5):e1002071. doi: 10.1371/journal.pgen.1002071. Epub 2011 May 26.
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Generation and characterization of a humanized PPARδ mouse model.
Br J Pharmacol. 2011 Sep;164(1):192-208. doi: 10.1111/j.1476-5381.2011.01359.x.

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