Taş Selim, Tuğcu Volkan, Mutlu Bircan, Karadağ Serdar, Bitkin Alper, Yücel Mehmet, Taşçi Ali Ihsan
Bakirkoy Dr. Sadi Konuk Training and Research Hospital, Istanbul, Turkey.
Arch Ital Urol Androl. 2011 Sep;83(3):141-6.
We investigated the incidence of ureteral stricture in patients treated with ureterorenoscopic pneumatic lithotripsy for distal ureteral calculi.
Between April 2006 and January 2009, 154 patients requiring ureterorenoscopic pneumatic lithotripsy for distal ureteral calculi were enrolled into the study. We evaluated the stone size, impaction of a stone, the need for ureteral orifice dilatation and the need for application of double-J stent.
A total of 154 patients underwent URS-PL for ureteral calculi. Mean calculi diameter was 12.17 +/- 2.54 (range: 5-20 mm). Stone free rates after the first URS-PL operation were 97.4% of patients. In 2 patients (1.29%), ureteral perforation occurred as an early complication. We observed deep mucosal injury in 9 patients (5.84%). Partial stricture (partial obstruction) was observed in 9 patients (5.84%). Of 9 patients who had an ureteral stricture postoperatively, 7 patients had ureteral calculi > or = 10 mm, 2 patients had calculi < 10 mm. We observed ureteral stricture in 2 (8.69%) out of 23 patients who had calculi < 10 mm, and in 7 (5.34%) out of 131 patients who had calculi > or = 10 mm (p > 0.05). Ureteral stricture was observed in 2 (13.33%) out of 15 patients who had impacted calculi, and in 7 (5.03%) out of 139 patients who did not have impacted calculi (p < 0.05). We observed ureteral stricture in 3 (6.25%) out of 48 patients who required ureteral dilatation, and in 6 (5.66%) out of 106 patients who did not require ureteral dilatation (p > 0.05). Ureteral stricture was observed in 6 (15%) out of 40 patients who required ureteral double-J catheter placement, and in 3 (2.63%) out of 114 patients who did not require ureteral double-J catheter placement (p < 0.05).
The results of our study have demonstrated that the success rate was not related to the stone dimension, but the time of operation was found to be increased with larger stones. Main risk factors for formation of ureteral stricture were impacted ureteral calculi and reasons which merits double-J catheter placement like mucosal damage, perforation, impacted calculi and high stone burden.
我们调查了接受输尿管镜气压弹道碎石术治疗输尿管下段结石患者输尿管狭窄的发生率。
2006年4月至2009年1月,154例因输尿管下段结石需行输尿管镜气压弹道碎石术的患者纳入本研究。我们评估了结石大小、结石嵌顿情况、输尿管口扩张的必要性以及双J支架置入的必要性。
共有154例患者接受了输尿管镜气压弹道碎石术治疗输尿管结石。结石平均直径为12.17±2.54(范围:5 - 20 mm)。首次输尿管镜气压弹道碎石术后结石清除率为97.4%。2例患者(1.29%)出现输尿管穿孔这一早期并发症。9例患者(5.84%)出现深部黏膜损伤。9例患者(5.84%)观察到部分狭窄(部分梗阻)。在术后发生输尿管狭窄的9例患者中,7例患者的输尿管结石≥10 mm,2例患者的结石<10 mm。我们观察到,在23例结石<10 mm的患者中有2例(8.69%)发生输尿管狭窄,在131例结石≥10 mm的患者中有7例(5.34%)发生输尿管狭窄(p>0.05)。在15例有结石嵌顿的患者中有2例(13.33%)发生输尿管狭窄,在139例无结石嵌顿的患者中有7例(5.03%)发生输尿管狭窄(p<0.05)。我们观察到,在48例需要输尿管扩张的患者中有3例(6.25%)发生输尿管狭窄,在106例不需要输尿管扩张的患者中有6例(5.66%)发生输尿管狭窄(p>0.05)。在40例需要置入输尿管双J导管的患者中有6例(15%)发生输尿管狭窄,在114例不需要置入输尿管双J导管的患者中有3例(2.63%)发生输尿管狭窄(p<0.05)。
我们的研究结果表明,成功率与结石大小无关,但发现手术时间会随着结石增大而增加。输尿管狭窄形成的主要危险因素是输尿管结石嵌顿以及诸如黏膜损伤、穿孔、结石嵌顿和高结石负荷等需要置入双J导管的原因。