Zaoui Sanaa, Hakkou Farid, Filali Houda
Université Cadi Ayyad, Marrakech, Maroc.
Therapie. 2011 Nov-Dec;66(6):499-506. doi: 10.2515/therapie/2011067. Epub 2011 Dec 21.
To assess the knowledge of physicians about generic drugs and their prescribing habits, with a view to making proposals for developing the use of generic drug in Morocco.
Prospective study conducted among 100 physicians working in different sectors, using a questionnaire comprising 14 questions. The points raised in this questionnaire focused on assessing the knowledge of physicians about generic drugs, their prescribing habits, and their point of view towards the rights of substitution.
The prescription of generic medicines is more than 20% of drug prescriptions in less than half of doctors. For 68% of physicians, a generic is not always effective. When the definition of generic drug only 66% of physicians mentioned bioequivalence with the brand-name drug, and when the definition of bioequivalence, for almost half (51%) of physicians, a generic drug bioequivalent to the brand-name drug is a drug with the same half-life. Eighty-eight percent (88%) of the doctors prescribe generic drugs when lower cost is met. Seventy percent of physicians (70%) prescribe generics when bioequivalence is demonstrated with the brand-name drug. Sixty-eight percent (68%) of doctors are against the substitution because it presents an obstacle to their freedom of prescription.
In order to increase the use of generic drugs, better information for physicians is necessary. Other ways can be implemented, first establish the quality of Moroccan generic by bioequivalence studies and think about steps to put in place to encourage doctors and pharmacists to prescribe and dispense generic drugs, particularly the rights of substitution.
评估医生对通用名药物的了解及其处方习惯,以便为在摩洛哥推广通用名药物的使用提出建议。
对100名不同科室的医生进行前瞻性研究,使用包含14个问题的问卷。该问卷提出的要点集中在评估医生对通用名药物的了解、他们的处方习惯以及他们对替代权的看法。
不到一半的医生开具的通用名药物处方超过药物处方的20%。68%的医生认为通用名药物并非总是有效。在通用名药物的定义方面,只有66%的医生提到与品牌药的生物等效性;而在生物等效性的定义方面,近一半(51%)的医生认为与品牌药生物等效的通用名药物是具有相同半衰期的药物。88%的医生在成本较低时会开具通用名药物。70%的医生在通用名药物与品牌药具有生物等效性时会开具通用名药物。68%的医生反对替代,因为这对他们的处方自由构成了障碍。
为了增加通用名药物的使用,有必要为医生提供更好的信息。还可以采取其他措施,首先通过生物等效性研究确定摩洛哥通用名药物的质量,并考虑采取措施鼓励医生和药剂师开具和调配通用名药物,特别是替代权方面。