[儿童脑动静脉畸形的质子立体定向治疗经验]

[Experience of proton stereotactic therapy for cerebral arteriovenous malformations in children].

作者信息

Gerasimov S V, Vinogradov V M, Garmashov Iu A, Shalek R A

出版信息

Vestn Rentgenol Radiol. 2008 Jan-Feb(1):19-23.

Abstract

The authors present the results of proton stereotactic therapy (using continuous double-axis pendulum irradiation) in 27 children with cerebral arteriovenous malformations (AVM). At the moment of therapy, the children's age was 6 to 15 years. The volume of AVM was 0.2 to 31.2 cm3. The absorbed doses in the maximum of a dose field were 40 to 80 Gy. Complete AVM obliteration (the mean volume in the group was 3.03 cm3) was obtained in 11 (41%) patients. A 50% or more reduction in AVM volume (mean volume, 10.6 cm3) was seen in 8 (30%) patients. There was a less than 50% reduction in AVM volumes (mean volume 9.6 cm3) in 2 (7%) patients and no effect could be achieved in 6 (22%) (mean AMV volume 19.7 cm3).

摘要

作者介绍了27例患有脑动静脉畸形（AVM）儿童接受质子立体定向治疗（使用连续双轴摆线照射）的结果。治疗时，儿童年龄为6至15岁。AVM体积为0.2至31.2立方厘米。剂量场最大值处的吸收剂量为40至80戈瑞。11例（41%）患者实现了AVM完全闭塞（该组平均体积为3.03立方厘米）。8例（30%）患者的AVM体积减少了50%或更多（平均体积为10.6立方厘米）。2例（7%）患者的AVM体积减少不到50%（平均体积9.6立方厘米），6例（22%）患者未取得效果（平均AVM体积19.7立方厘米）。