Cone J E, Rosenberg J
Occupational Health Clinic, San Francisco General Hospital, CA 94110.
Occup Med. 1990 Jul-Sep;5(3):563-81.
Medical surveillance for carcinogens refers to the use of medical history, physical examinations, and laboratory examinations to detect medical effects of exposure to cancer-causing agents. Biomonitoring for carcinogens, in contrast, involves testing for changes in DNA or chromosomes, presence of mutagens in body fluids, or presence of markers of exposure in cells. This article evaluates the current medical surveillance and biomonitoring techniques to assess their utility as measures of potential exposure to and effects of carcinogens in the workplace.
致癌物的医学监测是指利用病史、体格检查和实验室检查来检测接触致癌物质的医学影响。相比之下,致癌物的生物监测涉及检测DNA或染色体的变化、体液中诱变剂的存在或细胞中接触标志物的存在。本文评估了当前的医学监测和生物监测技术,以评估它们作为衡量工作场所潜在接触致癌物及其影响的措施的效用。