Department of Nephrology, Dialysis and Transplantation, Fondazione IRCCS Policlinico San Matteo and University of Pavia, Pavia, Italy.
Urology. 2012 Mar;79(3):e44. doi: 10.1016/j.urology.2011.10.049. Epub 2011 Dec 19.
Early allograft calcifications after kidney transplantation (KT) have already been reported, but the clinical implications of this finding are not clear thus far. Patient-related factors such as age, gender, underlying renal disease, and dialytic modality, seem to be irrelevant. It has been postulated that factors promoting the development of metastatic calcifications, including elevated calcium phosphate product and severe secondary hyperparathyroidism, could play a causal role. Here we report a case of a KT patient who developed early kidney calcifications which were associated with severe allograft dysfunction.
肾移植(KT)后早期发生移植物钙化已有报道,但目前尚不清楚这一发现的临床意义。患者相关因素,如年龄、性别、基础肾脏疾病和透析方式,似乎并不相关。有人推测,促进转移性钙化发展的因素,包括钙磷乘积升高和严重的继发性甲状旁腺功能亢进,可能起因果作用。本文报告了一例 KT 患者发生早期肾钙化,其与严重的移植物功能障碍有关。