Department of Surgery, Institut Universitaire de Cardiologie et de Pneumologie de Québec, Québec, Québec, Canada.
Surg Obes Relat Dis. 2013 Jan-Feb;9(1):63-8. doi: 10.1016/j.soard.2011.10.021. Epub 2011 Nov 15.
In the past 10 years, most bariatric surgeries have seen an important reduction in the early complication rate, partly associated with the development of the laparoscopic approach. Our objective was to assess the current early complication rate associated with biliopancreatic diversion with duodenal switch (BPD-DS) since the introduction of a laparoscopic approach in our institution, a university-affiliated tertiary care center.
A consecutive series of 1000 patients who had undergone BPD-DS from November 2006 to January 2010 was surveyed. The primary endpoint was the mortality rate. The secondary endpoints were the major 30-day complication rate and hospital stay >10 days. The data are reported as a mean ± SD, comparing the laparoscopic (n = 228) and open (n = 772) groups.
The mean age of the patients was 43 ± 10 years (40 ± 10 years in the laparoscopy group versus 44 ± 10 years in the open group, P < .01). The preoperative body mass index was 51 ± 8 kg/m(2) (47 ± 7 laparoscopy versus 52 ± 8 kg/m(2) open, P < .01). The conversion rate in the laparoscopy group was 2.6%. There was 1 postoperative death (.1%) from a pulmonary embolism in the laparoscopy group. The mean hospital stay was shorter after laparoscopic surgery (6 ± 6 d versus 7 ± 9 d, P = .01), and a hospital stay >10 days was more frequent in the open group (4.4% versus 7%, P = .04). Major complications occurred in 7% of the patients, with no significant differences between the 2 groups (7% versus 7.4%, P = .1). No differences were found in the overall leak or intra-abdominal abscess rate (3.5% versus 4%, P = .1); however, gastric leaks were more frequent after open surgery (0% versus 2%, P = .02). During a mean 2-year follow-up, 1 additional death occurred from myocardial infarction, 2 years after open BPD-DS.
The early and late mortality rate of BPD-DS is low and comparable to that of other bariatric surgeries.
在过去的 10 年中,大多数减重手术的早期并发症发生率显著降低,这在一定程度上与腹腔镜技术的发展有关。我们的目的是评估自我们的机构(一家大学附属医院的三级保健中心)采用腹腔镜方法以来,胆胰分流十二指肠转位术(BPD-DS)的当前早期并发症发生率。
对 2006 年 11 月至 2010 年 1 月期间接受 BPD-DS 的 1000 例患者进行了连续调查。主要终点是死亡率。次要终点是 30 天主要并发症发生率和住院时间>10 天。数据以平均值±标准差表示,比较了腹腔镜(n=228)和开放(n=772)组。
患者的平均年龄为 43±10 岁(腹腔镜组为 40±10 岁,开放组为 44±10 岁,P<.01)。术前体重指数为 51±8kg/m2(腹腔镜组为 47±7kg/m2,开放组为 52±8kg/m2,P<.01)。腹腔镜组的转化率为 2.6%。腹腔镜组有 1 例术后死于肺栓塞(0.1%)。腹腔镜手术后的平均住院时间较短(6±6d 与 7±9d,P=.01),开放组的住院时间>10 天的比例较高(4.4%与 7%,P=.04)。7%的患者发生主要并发症,两组间无显著差异(7%与 7.4%,P=.1)。两组间整体漏出或腹腔脓肿发生率无差异(3.5%与 4%,P=.1);然而,开放手术后胃漏更为常见(0%与 2%,P=.02)。在平均 2 年的随访中,1 例开放 BPD-DS 术后 2 年死于心肌梗死。
BPD-DS 的早期和晚期死亡率低,与其他减重手术相当。