Medical Department, Innlandet Hospital Trust Lillehammer, Lillehammer, Norway.
Scand Cardiovasc J. 2012 Apr;46(2):76-80. doi: 10.3109/14017431.2011.653824. Epub 2012 Jan 23.
To investigate differences in prognosis after myocardial infarction (MI) in patients classified according to the old and new definitions of MI. Patients not fulfilling the old definitions were classified as having a micro MI.
Data on 1216 consecutive patients with a diagnosis of first MI (38.3% women) and who were discharged from or died in one hospital in the 5-year period from 2001 were included in the study. Surviving patients were followed for a mean of 8.2 years. Risk factors and death after MI were analysed according to MI classification.
Of the patients, 20.1% were classified as having a micro MI. During follow-up, 47.2% of all the patients died. Patients with micro MI were older and fewer were current smokers than patients with other MI. In multivariate Cox regression analysis for the total risk of mortality, age, diabetes mellitus, a positive smoking history, history of stroke and living alone were significantly related to long-term prognosis, and there was no difference in long-term survival between the two types of MI (p 0.50).
After adjustment for confounders, patients with micro MI had no significant difference in long-term survival compared with those with other MI.
探讨根据心肌梗死(MI)的新旧定义分类后,患者预后的差异。不符合旧定义的患者被归类为微小心肌梗死。
本研究纳入了来自一家医院 2001 年 5 年内连续收治的 1216 例首次诊断为 MI 的患者(38.3%为女性)的资料,这些患者出院或在该医院死亡。存活患者的平均随访时间为 8.2 年。根据 MI 分类分析 MI 后的危险因素和死亡情况。
20.1%的患者被归类为微小心肌梗死。在随访期间,所有患者中有 47.2%死亡。与其他 MI 患者相比,微小心肌梗死患者年龄更大,当前吸烟者比例更低。多变量 Cox 回归分析总死亡率的全因风险,年龄、糖尿病、阳性吸烟史、卒中史和独居与长期预后显著相关,两种 MI 类型之间的长期生存率无差异(p>0.50)。
在调整了混杂因素后,微小心肌梗死患者与其他 MI 患者的长期生存率无显著差异。