利用异戊烯基化合物和代谢前体提高三轮藻产番茄红素。
Improved lycopene production by Blakeslea trispora with isopentenyl compounds and metabolic precursors.
机构信息
State Key Laboratory of Chemical Resource Engineering, College of Life Science and Technology, Beijing University of Chemical Technology, P.O. Box 75, 15 Beisanhuan East Road, Beijing, 100029, People's Republic of China.
出版信息
Biotechnol Lett. 2012 May;34(5):849-52. doi: 10.1007/s10529-011-0839-6. Epub 2011 Dec 30.
The highest lycopene production in mated cultures of Blakeslea trispora was 578 mg/l by adding 42 mg geraniol/l to the medium after 48 h of growth. The control gave 317 mg/l. Adding isopentenyl alcohol at 40 mg/l, mevalonic acid at 17.5 mg/l or dimethyl allyl alcohol at 150 mg, each after 36 h growth, gave lycopene yields 62, 45 and 47%, respectively, higher than the control.
交配培养的布拉氏蛇孢霉最高番茄红素产量为 48 小时后向培养基中添加 42 毫克香叶醇，达到 578 毫克/升。对照组为 317 毫克/升。添加 40 毫克/升异戊烯醇、17.5 毫克/升甲羟戊酸或 150 毫克/升二甲基烯丙醇，分别在生长 36 小时后添加，番茄红素产量分别比对照组高 62%、45%和 47%。
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