Department of Psychiatry, Neurobiology, Pharmacology and Biotechnology, School of Medicine, University of Pisa, Pisa, Italy.
Arch Womens Ment Health. 2012 Feb;15(1):39-47. doi: 10.1007/s00737-011-0246-y. Epub 2012 Jan 4.
The aim of this study was to assess suicidality in a non-clinical sample during the perinatal period and to report suicidality rates in women with major or minor depressive episode (MmD), assessed with the SCID, during the perinatal period. Women (1,066) were recruited at the third month of pregnancy and followed until the 12th month postpartum (N = 500). Suicidality was assessed with the MOODS-SR and with item 10 of the EPDS at different time-points during the perinatal period. The period prevalence of suicidality was 6.9% (95% CI: 6.0-7.8) during pregnancy and 4.3% (95% CI: 3.4-5.2) during postpartum, assessed with the MOODS-SR, and was 12.0% (95% CI: 10.8-13.2) during pregnancy and 8.6% (95% CI: 7.4-9.8) during the postpartum period, assessed with the EPDS. The prevalence of suicidality in women who had MmD during pregnancy was 26.4% and 34.1%, assessed with the MOODS-SR and the EPDS, respectively, while it was 18.4% (MOODS-SR) and 30.6% (EPDS) during the postpartum period. Clinicians should assess suicidality in women presenting with MmD during the whole perinatal period. Furthermore, suicidality should be assessed in women with a previous history of psychiatric disorder that reported a lifetime suicidal ideation.
本研究旨在评估围产期非临床样本中的自杀倾向,并报告围产期患有 Major 或 Minor 抑郁发作(MmD)的女性的自杀倾向发生率,采用 SCID 进行评估。共有 1066 名女性在妊娠第三个月入组,并随访至产后第 12 个月(N=500)。在围产期的不同时间点,使用 MOODS-SR 和 EPDS 的第 10 项评估自杀倾向。使用 MOODS-SR 评估,妊娠期间自杀倾向的时点患病率为 6.9%(95%CI:6.0-7.8),产后为 4.3%(95%CI:3.4-5.2);使用 EPDS 评估,妊娠期间自杀倾向的时点患病率为 12.0%(95%CI:10.8-13.2),产后为 8.6%(95%CI:7.4-9.8)。在妊娠期间患有 MmD 的女性中,使用 MOODS-SR 和 EPDS 评估的自杀倾向发生率分别为 26.4%和 34.1%,而在产后分别为 18.4%(MOODS-SR)和 30.6%(EPDS)。临床医生应在整个围产期评估患有 MmD 的女性的自杀倾向。此外,应评估有既往精神障碍病史并报告有过自杀意念的女性的自杀倾向。