人类烟碱型乙酰胆碱受体基因的定位：α和δ亚基基因定位于2号染色体，β亚基基因定位于17号染色体。

Assignment of the human nicotinic acetylcholine receptor genes: the alpha and delta subunit genes to chromosome 2 and the beta subunit gene to chromosome 17.

作者信息

Beeson D, Jeremiah S, West L F, Povey S, Newsom-Davis J

机构信息

Institute for Molecular Medicine, John Radcliffe Hospital, Oxford.

出版信息

Ann Hum Genet. 1990 Jul;54(3):199-208. doi: 10.1111/j.1469-1809.1990.tb00378.x.

DOI:10.1111/j.1469-1809.1990.tb00378.x

PMID:2221824

Abstract

The chromosomal assignments of the genes coding for the alpha, beta and delta subunits of the human nicotinic acetylcholine receptor have been determined from a panel of somatic cell hybrids and by direct in situ hybridization. The results localize CHRNA to 2q24-2q32. CHRNB to 17p11-17p12, and CHRND to chromosome 2q33-2qter.

摘要

通过一组体细胞杂种并采用直接原位杂交技术，已确定了编码人烟碱型乙酰胆碱受体α、β和δ亚基的基因的染色体定位。结果将CHRNA定位于2q24 - 2q32，CHRNB定位于17p11 - 17p12，CHRND定位于2q33 - 2q末端。