Grüngreiff K
Klinik für Innere Medizin, Medizinischen Akademie Magdeburg.
Gastroenterol J. 1990;50(2):82-7.
59 patients with exogenous liver coma in state III-IV were treated from 1980 to 1989 in our clinic. Incidence and complications in these patients were evaluated retrospectively. The most frequent eliciting factors were gastrointestinal bleeding, infections and acute alcohol excess, more than 2/3 of them having severe portal hypertension with ascites and esophageal varices at the time. Altogether 55 of the 59 liver coma patients died. The most important complications were, beside bleeding and infections, disturbances of the renal function and of the coagulation. Severe acute or chronic liver injury is often associated with multiorgan failure.
1980年至1989年期间,我院对59例处于III-IV期的外源性肝昏迷患者进行了治疗。对这些患者的发病率和并发症进行了回顾性评估。最常见的诱发因素是胃肠道出血、感染和急性酒精过量,其中超过2/3的患者当时患有严重的门静脉高压伴腹水和食管静脉曲张。59例肝昏迷患者中共有55例死亡。除出血和感染外,最重要的并发症是肾功能和凝血功能障碍。严重的急性或慢性肝损伤常伴有多器官功能衰竭。