Zhu Jianxin, Wang Yue, Deng Juncai, Lü Bo, Hao Peng
Department of Orthopaedics, Sichuan Provincial People's Hospital, Chengdu Sichuan 610071, PR China.
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2011 Nov;25(11):1335-8.
To study the effectiveness of avascular necrosis of the femoral head treated by lesions clearance,
Between March 2008 and May 2010, 14 patients (16 compact bone grafting, and porous tantalum rod implantation. hips) with avascular necrosis of the femoral head were treated by lesions clearance, compact bone grafting, and implantation of porous tantalum rod. Of 15 cases, 13 were male (15 hips) and 1 was female (1 hip) with a median age of 42.2 years (range, 18-73 years), including traumatic in 1 case (1 hip), alcoholic in 4 cases (4 hips), and steroid-induced in 9 cases (11 hips); 3 hips were at Association Research Circulation Osseous (ARCO) stage I and 13 hips were at ARCO stage II. The Harris score was 51.89 +/- 12.42, and the X-ray score was 31.88 +/- 4.03. All the cases were diagnosed by X-ray films and MRI. The median disease duration was 2.5 years (range, 6 months to 7 years). All the patients accepted the operation of lesions clearance by slotting at the neck of femur, then, compact bone grafting, and implantation of porous tantalum rod were performed. The affected limb could not bear weight loading at 1-3 months after operation and partly bear weight loading after 3 months of operation.
Primary healing of incision was achieved in all patients and no complication occurred. The patients were followed up 24 months on average (range, 13-36 months). Two patients underwent total hip arthroplasty at 4 months and 2 years respectively because of even worsened pain and collapsed femoral heads; 12 patients achieved obvious pain relief with a survival rate 87.5% (14/16). The postoperative Harris score was 84.89 +/- 17.96, showing significant difference when compared with preoperative score (t = -8.038, P = 0.001). The X-ray examination showed definite ossification, increased density, regular arrangement of the trabeculae and no collapsed femoral head. The X-ray score was 32.19 +/- 6.57, showing no significant difference when compared with preoperative score (t = -2.237, P = 0.819).
Lesions clearance, compact bone grafting, and implantation of porous tantalum rod for avascular necrosis of the femoral head have a good short-term clinical result.
研究病灶清除术治疗股骨头缺血性坏死的有效性。
2008年3月至2010年5月,对14例(16髋)股骨头缺血性坏死患者采用病灶清除、致密骨移植及多孔钽棒植入术治疗。15例中,男13例(15髋),女1例(1髋),中位年龄42.2岁(18 - 73岁),其中创伤性1例(1髋),酒精性4例(4髋),激素性9例(11髋);3髋为国际骨循环研究会(ARCO)I期,13髋为ARCO II期。Harris评分51.89±12.42,X线评分31.88±4.03。所有病例均经X线片及MRI确诊。中位病程2.5年(6个月至7年)。所有患者均接受股骨颈开槽病灶清除术,然后进行致密骨移植及多孔钽棒植入。术后1 - 3个月患侧肢体不负重,3个月后部分负重。
所有患者切口均一期愈合,无并发症发生。患者平均随访24个月(13 - 36个月)。2例患者分别于术后4个月和2年因疼痛加重、股骨头塌陷行全髋关节置换术;12例患者疼痛明显缓解,生存率87.5%(14/16)。术后Harris评分为84.89±17.96,与术前评分比较差异有统计学意义(t = -8.038,P = 0.001)。X线检查显示有明确骨化,密度增加,骨小梁排列规则,无股骨头塌陷。X线评分为32.19±6.57,与术前评分比较差异无统计学意义(t = -2.237,P = 0.819)。
病灶清除、致密骨移植及多孔钽棒植入治疗股骨头缺血性坏死近期临床效果良好。