Tuberculosis Program Evaluation and Research Unit, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada.
Int J Tuberc Lung Dis. 2012 Jan;16(1):43-9, i. doi: 10.5588/ijtld.11.0374.
To compare and interpret tuberculosis (TB) incidence rates in a Canadian population across two decennials (1989-1998 and 1999-2008) as a benchmark for World Health Organization targets and the long-term goal of TB elimination. The population under study was served by two urban clinics in the first decennial and two urban and one provincial clinic in the second.
TB rates among Status Indians, Canadian-born 'others' and the foreign-born were estimated using provincial and national databases. Program performance was measured in on-reserve Status Indians in each decennial.
In each decennial, the incidence rate in Status Indians and the foreign-born was greater than that in the Canadian-born 'others'; respectively 27.7 and 33.0 times in Status Indians, and 8.0 and 20.9 times in the foreign-born. Between decennials, the rate fell by 56% in Status Indians, 58% in Canadian-born 'others', and 18% in the foreign-born. On-reserve Status Indians had higher rates than off-reserve Status Indians, and the three-clinic model out-performed the two-clinic model among those on-reserve. Rates in the foreign-born varied by World Bank region, and were highest among those from Africa and Asia.
Status Indians and the foreign-born are at increased risk of TB in Canada. Significant progress towards TB elimination has been made in Status Indians but not in the foreign-born.
通过比较和解释两个十年(1989-1998 年和 1999-2008 年)期间加拿大人群中的结核病(TB)发病率,为世界卫生组织的目标和消除结核病的长期目标提供基准。研究人群由第一个十年的两个城市诊所和第二个十年的两个城市和一个省级诊所提供服务。
使用省级和国家级数据库估算第一和第二个十年期间的印度裔居民、加拿大出生的“其他人”和外国出生者的结核病发病率。每个十年都对保留地的印度裔居民进行了计划绩效评估。
在每个十年中,印度裔居民和外国出生者的发病率均高于加拿大出生的“其他人”;印度裔居民分别为 27.7 倍和 33.0 倍,外国出生者分别为 8.0 倍和 20.9 倍。在两个十年之间,印度裔居民的发病率下降了 56%,加拿大出生的“其他人”下降了 58%,外国出生者下降了 18%。保留地的印度裔居民的发病率高于非保留地的印度裔居民,而在保留地的居民中,三诊所模式的表现优于两诊所模式。外国出生者的发病率因世界银行地区而异,其中来自非洲和亚洲的外国出生者的发病率最高。
在加拿大,印度裔居民和外国出生者患结核病的风险增加。在印度裔居民中,消除结核病的工作取得了重大进展,但在外国出生者中没有取得进展。