Low density lipoprotein S-homocysteinylation is increased in acute myocardial infarction patients.

OBJECTIVES

We have investigated on the levels of homocysteine linked to LDL in acute myocardial infarction patients.

DESIGN AND METHODS

We used capillary electrophoresis to measure LDL-bound thiols in 16 AMI individuals and 32 healthy volunteers.

RESULTS

We found a significant increase of apo-B homocysteine and cysteine levels in LDL fraction of AMI subjects.

CONCLUSIONS

Our findings suggest that also LDL S-homocysteinylation may be considered among the markers for the CVD risk evaluation.