[支原体肺炎脑炎伴基底节坏死]
[Mycoplasma pneumoniae encephalitis associated with basal ganglia necrosis].
作者信息
El Hafidi N, Allouch B, Benbrahim F, Chellaoui M, El Mahraoui C
机构信息
Service de pathologie infectieuse et de pneumo-allergologie pédiatrique, hôpital Enfant Rabat, rue Famfdal Cherkaoui Rabat-Instituts, BP 6527, Rabat, Morocco.
出版信息
Rev Neurol (Paris). 2012 Jan;168(1):49-52. doi: 10.1016/j.neurol.2011.01.023. Epub 2012 Jan 14.
INTRODUCTION
Severe central nervous system diseases, such as encephalitis, have been reported in association with Mycoplasma pneumoniae infections.
CASE REPORT
A previously healthy 5-year-old boy presented with an atypical pneumonia; he rapidly developed encephalitis revealed by lethargy, generalized status epilepticus. MRI showed abnormal signals in the basal ganglia, typical of bilateral striatal necrosis. Serologic tests for M. pneumoniae were positive, the child recovered almost completely.
CONCLUSION
M. pneumoniae infection should be considered in all cases of acute encephalopathy; yet the pathogenesis of the disorder is unknown and the treatment uncertain.
引言
据报道，严重的中枢神经系统疾病，如脑炎，与肺炎支原体感染有关。
病例报告
一名此前健康的5岁男孩出现非典型肺炎；他迅速发展为脑炎，表现为嗜睡、全身性癫痫持续状态。磁共振成像显示基底神经节有异常信号，典型的双侧纹状体坏死。肺炎支原体血清学检测呈阳性，患儿几乎完全康复。
结论
在所有急性脑病病例中均应考虑肺炎支原体感染；然而，该疾病的发病机制尚不清楚，治疗方法也不确定。
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