Department of Communications and Auditory Neuroscience, House Research Institute, Los Angeles, California, USA.
Laryngoscope. 2012 Mar;122(3):645-8. doi: 10.1002/lary.22491. Epub 2012 Jan 17.
Auditory brainstem implants (ABIs) can provide highly beneficial hearing sensations to individuals deafened by bilateral vestibular schwannomas (neurofibromatosis type 2). Relatively little is known about the status of stimulated neurons after long-term ABI use. Direct examination of the cochlear nuclear complex (CN) of one 5-year ABI user indicated no deleterious effect. Recently, we examined the brainstem of a patient who used his ABI daily for 15 years with excellent performance. There was good preservation of CN cell size, morphology, and packing density, a very favorable sign considering that a number of infants are now receiving ABIs.
听觉脑干植入物 (ABIs) 可为双侧听神经鞘瘤(神经纤维瘤病 2 型)致聋的个体提供非常有益的听觉感受。关于长期使用 ABI 后刺激神经元的状态,人们知之甚少。对一名使用 ABI 长达 5 年的患者的耳蜗核复合体 (CN) 进行直接检查表明没有不良影响。最近,我们检查了一位每天使用 ABI 长达 15 年且表现出色的患者的脑干。CN 细胞大小、形态和堆积密度保持良好,这是一个非常有利的迹象,因为现在有许多婴儿正在接受 ABI 治疗。