Sakurai Yasuyoshi, Uchida Michiko, Aiba Junko, Mimura Fumiaki, Yamaguchi Midori
Department of Anesthesia, Social Insurance Funabashi Central Hospital, Funabashi 273-8556.
Masui. 2011 Dec;60(12):1394-7.
A 32-year-old pregnant woman diagnosed with aplastic anemia was admitted for emergent caesarean delivery of 26th week of the gestation due to PIH (pregnancy-induced hypertension) and NRFS (non-reassuring fetal status). After compensating platelets counts to 5.3x10(4) microl-1, general anesthesia was induced with propofol and rocuronium. Anesthesia was maintained with O2 and sevoflurane until delivery and with modified-NLA after delivery. She was additionally monitored with Vigileo/FloTrac system (Edwards Lifesciences, USA) and TOF-WATCH SX (Nihon Kohden, Tokyo). After 8 minutes of operation her baby was born with the 5-minute Apgar score of 5 and the UA-pH of 7.387. It was only 2 hours and 12 minutes that the baby was born after she was admitted. The baby was tracheally intubated and transferred to NICU. Blood loss during operation was 835 g and two units of RCC was transfused. Circulatory values were kept acceptable and neuromuscular blocking was completely reversed by sugammadex and extubated in the operating room. Bleeding tendency and atonic bleeding were not observed. She survived perioperative period and was to be treated for aplastic anemia. Her baby was discharged neurologically free. We should be ready to respond to anesthetic requirement for urgent cases of aplastic anemia.
一名32岁被诊断为再生障碍性贫血的孕妇因妊娠高血压(PIH)和胎儿状况不佳(NRFS)入院,在妊娠26周时紧急行剖宫产。在将血小板计数补充至5.3×10⁴/微升后,用丙泊酚和罗库溴铵诱导全身麻醉。麻醉维持使用氧气和七氟醚直至分娩,分娩后使用改良的NLA。另外使用Vigileo/FloTrac系统(美国爱德华生命科学公司)和TOF-WATCH SX(日本光电,东京)对其进行监测。手术8分钟后,她的婴儿出生,5分钟阿氏评分5分,脐动脉血pH值为7.387。她入院后仅2小时12分钟婴儿就出生了。婴儿经气管插管后转入新生儿重症监护病房。术中失血835克,输注了两单位红细胞悬液。循环指标保持在可接受范围内,神经肌肉阻滞通过舒更葡糖完全逆转,并在手术室拔管。未观察到出血倾向和宫缩乏力性出血。她在围手术期存活下来,将接受再生障碍性贫血的治疗。她的婴儿出院时神经系统正常。我们应该随时准备应对再生障碍性贫血紧急病例的麻醉需求。