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[巨大听神经瘤的外科治疗结果]

[Results in the surgical treatment of giant acoustic neuromas].

作者信息

Giordano Ana Inés, Domènech Ivan, Torres Alberto, Skufca Javier, Callejo Angela, Palomino Laura, Aparicio Alberto, Junyent Josefina, Mañós Manuel

机构信息

Servicio Otorrinolaringología, Hospital Universitario de Bellvitge, L'Hospitalet de Llobregat, Barcelona, España.

出版信息

Acta Otorrinolaringol Esp. 2012 May-Jun;63(3):194-9. doi: 10.1016/j.otorri.2011.11.003. Epub 2012 Jan 20.

Abstract

INTRODUCTION AND OBJECTIVES

To compare the results obtained in the resection of 21 giant vestibular schwannomas via retrosigmoid (RS) and combined retrosigmoid/translabyrinthine (RS/TL) approaches with respect to intra- and postoperative complications, facial nerve preservation and postsurgical sequelae.

METHODS

This was a retrospective study of 21 patients who underwent a resection of a giant vestibular neuroma according to the Tos & Thomsen Scale (greater than or equal to 4 centimetres) in a tertiary care centre in the period between 2000 and 2008. We present the most significant characteristics of the series studied and the analysis of the advantages and inconveniences of each approach. We also analyse the results regarding facial nerve function preservation.

RESULTS

We highlight the absence of mortality in the 21-patient group. There were no important intraoperative complications. Total resection of the lesion was achieved in the 87% of the cases, with facial nerve preservation of 73% using the combined RS/TL approach, in comparison to 40% using the RS. Facial nerve function after two years was acceptable or good in 67% (including those with heteronerve anastomosis). A global percentage of 14.3% of cerebrospinal liquid fistula was observed, as well as 9.5% of meningitis.

CONCLUSIONS

The results of the study demonstrate that the combined retrosigmoid translabyrinthine approach for giant schwannoma treatment offers increased facial nerve preservation and lower morbidity, constituting an important option in the treatment of this kind of tumours thanks to a multidisciplinary approach.

摘要

引言与目的

比较经乙状窦后(RS)入路和乙状窦后/经迷路联合(RS/TL)入路切除21例巨大前庭神经鞘瘤在术中和术后并发症、面神经保留及术后后遗症方面的结果。

方法

这是一项对21例患者的回顾性研究,这些患者于2000年至2008年期间在一家三级医疗中心接受了根据托斯和汤姆森量表(大于或等于4厘米)诊断的巨大前庭神经瘤切除术。我们展示了所研究系列的最显著特征,以及对每种入路的优缺点分析。我们还分析了面神经功能保留方面的结果。

结果

我们强调21例患者组中无死亡病例。术中无重大并发症。87%的病例实现了病变的全切除,联合RS/TL入路面神经保留率为73%,而RS入路为40%。两年后面神经功能可接受或良好的比例为67%(包括那些进行了异神经吻合的患者)。观察到脑脊液漏的总体发生率为14.3%,脑膜炎发生率为9.5%。

结论

研究结果表明,联合乙状窦后经迷路入路治疗巨大神经鞘瘤可提高面神经保留率并降低发病率,由于采用了多学科方法,构成了治疗这类肿瘤的重要选择。

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