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[冠状动脉循环的神经调节]

[Neural regulation of coronary circulation].

作者信息

Khomaziuk A I

出版信息

Fiziol Zh SSSR Im I M Sechenova. 1979 Apr;65(4):589-97.

PMID:222634
Abstract

In anesthetized dogs, with the aid of catheterization and perfusion of the coronary arteries roith heporinesed blood, catheterization of the heart cavities, and synchronous recording of the hemodynamics in unopened thorax, the mechanisms of neural regulation of the coronary circulation were analysed. Tonic effects of the nervous system on the coronary vessels are insignificant, coronary resistance being maintained by the high basal tonus. The cholinergic and adrenergic mechaniseins interact with the more powerful metabolic mechanisms. The concrete interrelationships between the cholinergic and the adrenergic mechanisms in the heart adrenergic responses as well as their probable physiological significance, are discussed.

摘要

在麻醉犬身上,借助冠状动脉插管并用肝素化血液进行灌注、心脏腔室插管以及在未打开胸腔的情况下同步记录血流动力学,分析了冠状动脉循环的神经调节机制。神经系统对冠状动脉的紧张性作用不显著,冠状动脉阻力由高基础张力维持。胆碱能和肾上腺素能机制与更强大的代谢机制相互作用。讨论了心脏肾上腺素能反应中胆碱能和肾上腺素能机制之间的具体相互关系及其可能的生理意义。

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