Paul K P, Toomes H, Vogt-Moykopf I
Universitätskinderklinik, Heidelberg, Federal Republic of Germany.
Eur J Pediatr. 1990 Sep;149(12):862-5. doi: 10.1007/BF02072075.
Pulmonary function was evaluated before and after 15 operations for resection of pulmonary metastases from osteogenic sarcoma. In the whole study group (ten patients, aged 13-18 years) preoperative vital capacity (VC) ranged from 62% to 122% (mean 83%) of predicted normal values for height. The operations were performed via median sternotomy. One-28 metastases were removed per session. Six months after the operations VC averaged nearly 95% of the preoperative values. Signs of bronchial obstruction or persistent pulmonary hyperinflation were only present in one patient with repeated operations. We conclude that resection of pulmonary metastases with limited loss of parenchyma leads to an almost complete recovery of preoperative pulmonary function parameters.
对15例骨肉瘤肺转移瘤切除术前后的肺功能进行了评估。在整个研究组(10例患者,年龄13 - 18岁)中,术前肺活量(VC)为预测正常身高值的62%至122%(平均83%)。手术通过正中胸骨切开术进行。每次手术切除1 - 28个转移瘤。术后6个月,VC平均接近术前值的95%。仅1例反复手术的患者出现支气管阻塞或持续性肺过度充气的体征。我们得出结论,切除肺转移瘤且实质损失有限会使术前肺功能参数几乎完全恢复。