Department of Orthopaedic Surgery, Seoul National University Bundang Hospital, Kyungki, South Korea.
Dev Med Child Neurol. 2012 Mar;54(3):231-9. doi: 10.1111/j.1469-8749.2011.04172.x. Epub 2012 Jan 23.
This study was undertaken to determine the need for concurrent prophylactic femoral varization osteotomy (FVO) of contralateral stable hips at the time of hip reconstructive surgery on unstable hips in non-ambulant individuals with cerebral palsy (Gross Motor Function Classification System levels IV and V).
A decision analysis model was constructed that included (1) the probability of unstable hips during observation of the contralateral stable hips, (2) unstable hip rate (subluxation or dislocation rate) after prophylactic FVO or after delayed reconstructive surgery (including FVO) for unstable hips, and (3) complication rates after concurrent prophylactic FVO or after hip reconstructive surgery. The final outcome score was based on pain utility measures. The probabilities of all cases and the utility score were obtained by literature review.
The decision model favoured concurrent prophylactic FVO for the contralateral stable hips over observation (pain utility measure scores 0.814 vs 0.781). In a one-way sensitivity analysis, the decision model favoured concurrent prophylactic FVO when the unstable hip rate of contralateral stable hips during observation was 27% or over. Concurrent prophylactic surgery also demonstrated higher utility scores than observation when the unstable hip rate after FVO was between 0% and 29%.
The decision analysis model demonstrated that concurrent prophylactic FVO for a contralateral stable hip in individuals with cerebral palsy undergoing hip reconstructive surgery was beneficial from a medical perspective, which was based on current evidence.
本研究旨在确定在脑瘫患者(粗大运动功能分级系统 IV 级和 V 级)行髋关节重建手术时,是否需要同期行对侧稳定髋关节预防性股骨旋转截骨术(FVO)。
构建了一个决策分析模型,包括(1)观察对侧稳定髋关节时不稳定髋关节的概率,(2)预防性 FVO 后或不稳定髋关节延迟重建手术(包括 FVO)后的不稳定髋关节发生率(半脱位或脱位率),(3)同期行预防性 FVO 或髋关节重建手术后的并发症发生率。最终的结局评分基于疼痛效用测量值。所有病例的概率和效用评分均通过文献复习获得。
决策模型支持同期行对侧稳定髋关节预防性 FVO,而不是观察(疼痛效用测量评分 0.814 比 0.781)。在单因素敏感性分析中,当观察期间对侧稳定髋关节的不稳定髋关节发生率为 27%或更高时,决策模型支持同期行预防性 FVO。当 FVO 后不稳定髋关节发生率在 0%至 29%之间时,同期预防性手术的效用评分也高于观察。
决策分析模型表明,对于接受髋关节重建手术的脑瘫患者,同期行对侧稳定髋关节预防性 FVO 从医学角度来看是有益的,这是基于当前的证据。