阿托品作为仰卧位踏车超声心动图的辅助手段：一种达到目标心率或心率血压乘积的替代策略。

Atropine as an adjunct to supine bicycle stress echocardiography: an alternative strategy to achieve target heart rate or rate pressure product.

机构信息

Cardiac Noninvasive Laboratory, Cedars-Sinai Medical Center, 8700 Beverly Blvd, Room 5623, Los Angeles 90048, CA, USA.

出版信息

Eur Heart J Cardiovasc Imaging. 2012 Jul;13(7):612-6. doi: 10.1093/ejechocard/jer268. Epub 2012 Jan 6.

DOI:10.1093/ejechocard/jer268

PMID:22271103

Abstract

AIMS

To investigate the use of atropine to achieve target heart rate (THR) and rate pressure product (RPP) during supine bicycle exercise stress echocardiography (SBESE) to increase the number of diagnostic stress tests.

METHODS AND RESULTS

Forty-four patients that were unable to achieve THR or RPP during SBESE performed to evaluate ischaemia were given 0.4-1.2 mg of atropine to augment THR and RPP. After atropine (0.7 ± 0.3 mg) the maximum heart rate (HR) achieved was 133 (± 16) bpm, mean THR was 82% (± 8%), and average RPP was 22 716 (± 4915) b/min × mmHg. Of the patients with a non-diagnostic SBESE, with the use of atropine 80% of those patients achieved a diagnostic test. There were no major adverse affects from the administration of atropine.

CONCLUSION

The use of atropine to augment the HR or RPP during SBESE (i) is safe; (ii) enables the assessment of ischaemia at peak effort; and (iii) allows assessment of exercise haemodynamics in patients with sub-maximal exercise capacity and chronotropic incompetence.

摘要

目的

探讨在仰卧位自行车运动超声心动图（SBESE）中使用阿托品来达到目标心率（THR）和心率血压乘积（RPP），以增加诊断性应激测试的数量。

方法和结果

44 名在 SBESE 中无法达到 THR 或 RPP 以评估缺血的患者被给予 0.4-1.2 毫克的阿托品来增加 THR 和 RPP。使用阿托品（0.7 ± 0.3 毫克）后，最大心率（HR）达到 133（± 16）次/分，平均 THR 为 82%（± 8%），平均 RPP 为 22716（± 4915）次/分×mmHg。在非诊断性 SBESE 患者中，使用阿托品后，80%的患者达到了诊断性测试。阿托品的使用没有产生重大不良反应。