Zheng Zhi, Pan Youmin, Song Chaoguo, Wei Hao, Wu Shimin, Wei Xiang, Pan Tiecheng, Li Jun
Department of Cardiothoracic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Am Surg. 2012 Jan;78(1):133-7.
Focal organizing pneumonia is a unique form of organizing pneumonia. Little is known regarding its clinical and radiological feature, diagnosis, management, and outcome. Twenty patients with focal organizing pneumonia were investigated and compared with 40 patients with bronchogenic carcinoma. There were 38 men (63.3%) and 22 women (36.7%). The mean age was 55 ± 9.9 years. No specific feature in clinical and radiological manifestation was found to distinguish between focal organizing pneumonia and bronchogenic carcinoma. In patients with focal organizing pneumonia, wedge resection was performed in 12 cases and lobectomy in eight cases. Follow-up was complete with a median period of 26 months (range, 6 to 104 months). All patients were free from recurrence of organizing pneumonia. Clinical and radiologic findings of focal organizing pneumonia are nonspecific, and this unique form of organizing pneumonia is difficult to differentiate from lung cancer. Surgical resection allows both diagnosis and cure. However, considering the benign nature of this disease, major pulmonary resections should be avoided.
局灶性机化性肺炎是机化性肺炎的一种独特形式。关于其临床和放射学特征、诊断、治疗及预后，人们了解甚少。对20例局灶性机化性肺炎患者进行了研究，并与40例支气管源性癌患者进行了比较。其中男性38例（63.3%），女性22例（36.7%）。平均年龄为55±9.9岁。未发现临床和放射学表现中有可区分局灶性机化性肺炎和支气管源性癌的特异性特征。局灶性机化性肺炎患者中，12例行楔形切除术，8例行肺叶切除术。随访完整，中位随访期为26个月（范围6至104个月）。所有患者均无机化性肺炎复发。局灶性机化性肺炎的临床和放射学表现无特异性，这种独特形式的机化性肺炎难以与肺癌相鉴别。手术切除既能明确诊断又能治愈疾病。然而，考虑到该病的良性性质，应避免进行大范围肺切除术。
