肾移植后发生的上皮-肌上皮型腮腺癌。

Epithelial-myoepithelial parotid carcinoma after kidney transplantation.

作者信息

Horta R, Barreto F, Marques M, Rebelo M, Reis J C, Lopes J M, Amarante J M

机构信息

Department of Plastic, Aesthetic, Reconstructive, Maxilo-Facial Surgery, and Burn Unit, Hospital de São João, Porto, Portugal.

出版信息

Ecancermedicalscience. 2008;2:92. doi: 10.3332/ecancer.2008.92. Epub 2008 Aug 21.

DOI:10.3332/ecancer.2008.92

PMID:22275975

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3234068/

Abstract

The occurrence of a second malignant neoplasm (SMN) in patients who have been submitted to kidney transplantation is increasing and causes concern; parotid carcinoma is rarely reported after transplantation and may be related to long-term chemotherapy.Salivary gland carcinomas displaying exclusively myoepithelial differentiation-myoepithelial carcinomas (EMC) are rare, being less than 1% of all salivary gland tumours. EMC arises most commonly in the parotid gland and usually occurs in women. Their histopathologic features, immunohistochemical profile and clinical behaviour remain controversial.

摘要

接受肾移植的患者中发生第二原发性恶性肿瘤（SMN）的情况正在增加并引起关注；移植后腮腺癌很少见，可能与长期化疗有关。仅表现为肌上皮分化的涎腺癌——肌上皮癌（EMC）很罕见，占所有涎腺肿瘤的比例不到1%。EMC最常发生于腮腺，且通常发生在女性身上。它们的组织病理学特征、免疫组化特征和临床行为仍存在争议。