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[喉发育异常和癌的内镜诊断进展]

[Advances in endoscopic diagnosis of dysplasia and carcinoma of the larynx].

作者信息

Arens C, Vorwerk U, Just T, Betz C S, Kraft M

机构信息

Universitätsklinik für Hals-, Nasen- und Ohrenheilkunde, Universitätsklinikum Magdeburg A.ö.R, Leipziger Str. 44, 39120, Magdeburg, Deutschland.

出版信息

HNO. 2012 Jan;60(1):44-52. doi: 10.1007/s00106-011-2428-3.

DOI:10.1007/s00106-011-2428-3
PMID:22282010
Abstract

To improve the preoperative and intraoperative diagnosis of laryngeal cancer and its precursors, various endoscopic imaging techniques have been developed in recent years. These techniques differ markedly in their specific applications and goals. Precisely distinguishing among normal mucosa, dysplasia and invasive carcinoma with these procedures is necessary. Furthermore, the exact identification of tumor margins should be possible. The long-term goal is the development of optical biopsy. Since so far there have only been small studies regarding the evaluation of the presented methods, it is necessary to establish multi-center trials with large sample sizes to accurately estimate the value of these endoscopic imaging techniques.

摘要

为提高喉癌及其癌前病变的术前和术中诊断水平,近年来已开发出多种内镜成像技术。这些技术在其具体应用和目标上有显著差异。使用这些方法精确区分正常黏膜、发育异常和浸润性癌是必要的。此外,应能够准确识别肿瘤边缘。长期目标是开发光学活检技术。由于迄今为止关于所提出方法的评估仅有少量研究,因此有必要开展大样本量的多中心试验,以准确评估这些内镜成像技术的价值。

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1
[Advances in endoscopic diagnosis of dysplasia and carcinoma of the larynx].[喉发育异常和癌的内镜诊断进展]
HNO. 2012 Jan;60(1):44-52. doi: 10.1007/s00106-011-2428-3.
2
[Endoscopic imaging techniques in the diagnosis of laryngeal carcinoma and its precursor lesions].[内镜成像技术在喉癌及其癌前病变诊断中的应用]
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[Noninvasive imaging using autofluorescence endoscopy: Value for the early detection of laryngeal cancer].

本文引用的文献

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Value of fluorescence endoscopy for the early diagnosis of laryngeal cancer and its precursor lesions.荧光内镜在喉癌及其癌前病变早期诊断中的价值。
Head Neck. 2011 Jul;33(7):941-8. doi: 10.1002/hed.21565. Epub 2010 Nov 29.
2
[Ultrasound microscopy in the upper aerodigestive tract. Initial clinical experiences].[上呼吸道消化道的超声显微镜检查。初步临床经验]
HNO. 2011 Apr;59(4):366-70. doi: 10.1007/s00106-010-2248-x.
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Polarization-sensitive optical coherence tomography imaging of benign and malignant laryngeal lesions: an in vivo study.
[利用自体荧光内镜的非侵入性成像:对喉癌早期检测的价值]
HNO. 2016 Jan;64(1):13-8. doi: 10.1007/s00106-015-0095-5.
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[Fluorescence imaging in laryngology: Physical principles, clinical applications and study results].[喉科学中的荧光成像:物理原理、临床应用及研究结果]
HNO. 2016 Jan;64(1):4-12. doi: 10.1007/s00106-015-0098-2.
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Transoral treatment strategies for head and neck tumors.头颈部肿瘤的经口治疗策略。
GMS Curr Top Otorhinolaryngol Head Neck Surg. 2012;11:Doc05. doi: 10.3205/cto000087. Epub 2012 Dec 20.
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[Endoscopy of the larynx by hyperspectral imaging].[通过高光谱成像进行喉部内窥镜检查]
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偏振敏感光学相干断层成像术对良恶性喉病变的活体研究。
Otolaryngol Head Neck Surg. 2011 Jul;145(1):91-9. doi: 10.1177/0194599811403078.
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Endoscopic diagnosis of laryngeal cancer and precancerous lesions by narrow band imaging.窄带成像技术在内镜下诊断喉癌及癌前病变
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Optical coherence tomography allows for the reliable identification of laryngeal epithelial dysplasia and for precise biopsy: a clinicopathological study of 61 patients undergoing microlaryngoscopy.光学相干断层扫描可可靠地区分喉上皮异型增生,并能进行精确的活检:61 例行显微喉镜检查患者的临床病理研究。
Laryngoscope. 2010 Oct;120(10):1964-70. doi: 10.1002/lary.21057.
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Opt Express. 2010 Jul 5;18(14):14644-53. doi: 10.1364/OE.18.014644.
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J Biomed Opt. 2010 Mar-Apr;15(2):026014. doi: 10.1117/1.3314898.
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Rigid confocal endoscopy for in vivo imaging of experimental oral squamous intra-epithelial lesions.刚性共聚焦内镜用于实验性口腔鳞状上皮内病变的体内成像。
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Eur Arch Otorhinolaryngol. 2010 Mar;267(3):409-14. doi: 10.1007/s00405-009-1121-6. Epub 2009 Oct 14.
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