Arens C, Vorwerk U, Just T, Betz C S, Kraft M
Universitätsklinik für Hals-, Nasen- und Ohrenheilkunde, Universitätsklinikum Magdeburg A.ö.R, Leipziger Str. 44, 39120, Magdeburg, Deutschland.
HNO. 2012 Jan;60(1):44-52. doi: 10.1007/s00106-011-2428-3.
To improve the preoperative and intraoperative diagnosis of laryngeal cancer and its precursors, various endoscopic imaging techniques have been developed in recent years. These techniques differ markedly in their specific applications and goals. Precisely distinguishing among normal mucosa, dysplasia and invasive carcinoma with these procedures is necessary. Furthermore, the exact identification of tumor margins should be possible. The long-term goal is the development of optical biopsy. Since so far there have only been small studies regarding the evaluation of the presented methods, it is necessary to establish multi-center trials with large sample sizes to accurately estimate the value of these endoscopic imaging techniques.
为提高喉癌及其癌前病变的术前和术中诊断水平,近年来已开发出多种内镜成像技术。这些技术在其具体应用和目标上有显著差异。使用这些方法精确区分正常黏膜、发育异常和浸润性癌是必要的。此外,应能够准确识别肿瘤边缘。长期目标是开发光学活检技术。由于迄今为止关于所提出方法的评估仅有少量研究,因此有必要开展大样本量的多中心试验,以准确评估这些内镜成像技术的价值。