Heath Alana J, Day Christopher P, Buckenham Timothy M
Department of Radiology, Christchurch Hospital, Christchurch, New Zealand.
ANZ J Surg. 2011 Oct;81(10):713-6. doi: 10.1111/j.1445-2197.2010.05600.x.
Infective thoracic aneurysms are rare and have a poor prognosis. In the past, these have been managed surgically with adjunctive antibiotic therapy. Endoluminal repair is a relatively new treatment option which may be associated with lower morbidity and mortality.
The New Zealand Thoracic Aorta Stent graft registry was interrogated between December 2001 and September 2009, selecting all patients with endoluminal repair of infective thoracic aortic aneurysms.
Out of 184 patients on the database, four (2.2%) patients (male = 3, median age = 72) underwent endoluminal repair of an infective thoracic aortic aneurysm. The aneurysm was successfully excluded at the time of the procedure in all patients. There was a low incidence of post-procedural complications including atrial fibrillation (n = 1), pneumonia with haemoptysis (n = 1), urinary retention (n = 1) and access site seroma (n = 1). Time to discharge was mean of 26.5 days, median 22.5 days (8–53 days). One of the four patients is still alive and well at the time of reporting. Of the remaining three patients, mean survival is 486 days, median 374 days (336–748 days).
Endoluminal repair is a treatment option for infective thoracic aneurysms, but the durability is unknown. Due to the rareness of the condition, a randomized clinical trial is unlikely to succeed. National registries such as the New Zealand Thoracic Aortic Stent provide useful information regarding this.
感染性胸主动脉瘤较为罕见,预后较差。过去,此类疾病通过手术联合抗生素治疗。腔内修复是一种相对较新的治疗选择,可能具有较低的发病率和死亡率。
对2001年12月至2009年9月期间的新西兰胸主动脉支架移植物登记处进行查询,选取所有接受感染性胸主动脉瘤腔内修复的患者。
在数据库中的184例患者中,4例(2.2%)患者(男性3例,中位年龄72岁)接受了感染性胸主动脉瘤的腔内修复。所有患者在手术时动脉瘤均成功被隔绝。术后并发症发生率较低,包括房颤(1例)、咯血性肺炎(1例)、尿潴留(1例)和穿刺部位血清肿(1例)。出院时间平均为26.5天,中位数为22.5天(8 - 53天)。在报告时,4例患者中有1例仍然存活且状况良好。其余3例患者的平均生存期为486天,中位数为374天(336 - 748天)。
腔内修复是感染性胸主动脉瘤的一种治疗选择,但耐久性未知。由于该疾病罕见,随机临床试验不太可能成功。像新西兰胸主动脉支架登记处这样的国家登记处提供了有关此方面的有用信息。