曲马多撤市对其他具有滥用潜力的处方药物使用的影响。
Effect of the market withdrawal of carisoprodol on use of other prescribed drugs with abuse potential.
机构信息
Department of Pharmacoepidemiology, Norwegian Institute of Public Health, Oslo, Norway.
出版信息
Clin Pharmacol Ther. 2012 Mar;91(3):438-41. doi: 10.1038/clpt.2011.250. Epub 2012 Feb 8.
Carisoprodol, a centrally acting muscle relaxant indicated for acute lower back pain, has been available in Europe and the United States since 1959. Studies indicating increased risk of abuse or addiction led to withdrawal of the drug from the market in Norway and other EU countries in 2008. In this nationwide longitudinal prescription study of 53,116 individuals in Norway, previous users of carisoprodol switched, to a limited extent, to other prescribed drugs with abuse potential after the withdrawal.
卡立普多，一种中枢作用的肌肉松弛剂，用于治疗急性腰痛，自 1959 年以来就在欧洲和美国使用。一些研究表明，该药有更高的滥用或成瘾风险，这导致该药在 2008 年从挪威和其他欧盟国家的市场撤出。在挪威一项涉及 53116 人的全国性纵向处方研究中，在该药撤出后，有一定程度的卡立普多先前使用者转而使用其他有滥用潜力的处方药物。
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