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扁桃体周围脓肿的循证综述。

An evidence-based review of peritonsillar abscess.

机构信息

Department of Otolaryngology Head and Neck Surgery, Freeman Hospital, Newcastle upon Tyne, UK.

出版信息

Clin Otolaryngol. 2012 Apr;37(2):136-45. doi: 10.1111/j.1749-4486.2012.02452.x.

Abstract

OBJECTIVE OF REVIEW

We present the current literature surrounding peritonsillar abscess management highlighting areas of controversy. TYPE OF REVIEW AND SEARCH STRATEGY: Literature review using Medline and Embase databases (search terms 'peritonsillar abscess', 'peritonsillar infection' and 'quinsy') limited to articles published from 1991 to 2011 (English language).

RESULTS

(i)

INVESTIGATIONS

Intraoral ultrasound has a sensitivity and specificity of between 89-95% and 79-100%, respectively, for correctly diagnosing peritonsillar abscess and is underutilised currently. (ii) Medical management: Steroids can effectively aid recovery, reducing hospitalisation time and improving symptom relief; however, further study is needed, especially related to risk and cost benefit. Penicillin and metronidazole are an effective combination in 98-99% of cases of peritonsillar abscess. (iii) Surgical management: Overall, there is no convincing evidence in favour of either aspiration or incision & drainage. Quinsy tonsillectomy is subject to great geographical variation, however, is a safe procedure and reduces overall recovery time when compared with interval tonsillectomy. (iv) Admission: peritonsillar abscess can be effectively managed as an outpatient in many cases. (v) Further management: Overall, the recurrence rate of peritonsillar abscess is poorly defined but estimated as 9-22% based on current evidence. Interval tonsillectomy may be indicated in selected groups of patients at high risk of recurrence.

CONCLUSIONS

Peritonsillar abscess is a common condition with increasing incidence. We demonstrate the potential for evidence-based modifications in clinical management. However, lack of national consensus may mean that this evidence base is not being adequately exploited in current practice. A national audit of peritonsillar abscess management, in particular looking at recurrence rates and patient experience with different management strategies, appears indicated.

摘要

目的综述

本文旨在呈现目前关于扁桃体周围脓肿治疗的文献,重点讨论争议领域。

类型综述及检索策略

文献检索采用 Medline 和 Embase 数据库(检索词为“peritonsillar abscess”“peritonsillar infection”和“quinsy”),限定 1991 年至 2011 年发表的文献(英语)。

结果

(一)检查:口腔内超声检查诊断扁桃体周围脓肿的敏感性和特异性分别为 89-95%和 79-100%,但目前使用率较低。(二)内科治疗:皮质类固醇能有效促进康复,减少住院时间,缓解症状;但仍需进一步研究,尤其是关于风险和成本效益。青霉素和甲硝唑联合治疗扁桃体周围脓肿的有效率为 98-99%。(三)外科治疗:目前,尚无令人信服的证据支持脓肿穿刺抽吸或切开引流术。扁桃体周围脓肿切开排脓术在不同地区的应用差异较大,但与择期扁桃体切除术相比,其能显著缩短总体康复时间,是一种安全的术式。(四)住院:在许多情况下,扁桃体周围脓肿可作为门诊患者进行有效治疗。(五)进一步治疗:目前,基于现有证据,扁桃体周围脓肿的复发率难以明确界定,但估计为 9-22%。对于有高复发风险的特定患者群体,可能需要行扁桃体切除术。

结论

扁桃体周围脓肿是一种常见疾病,发病率不断上升。我们展示了在临床管理方面进行基于证据的修改的潜力。但是,缺乏全国共识可能意味着目前在实践中尚未充分利用这一证据基础。需要对扁桃体周围脓肿的治疗进行全国性的评估,特别是要关注不同治疗策略的复发率和患者体验。

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