Suder Natalie C, Wukich Dane K
UPMC Comprehensive Foot and Ankle Center, Pittsburgh, PA 15203, USA.
Foot Ankle Spec. 2012 Apr;5(2):97-101. doi: 10.1177/1938640011434502. Epub 2012 Feb 8.
The aim of this prospective study was to determine the prevalence of neuropathy in diabetic patients undergoing foot and ankle surgery. It was hypothesized that the prevalence of diabetic neuropathy is higher among patients who undergo foot and ankle surgery compared with historical rates of neuropathy in diabetic patients in general.
During a consecutive 42-month period, patient data were prospectively entered for 1859 consecutive patients undergoing foot and ankle surgery. Among the subjects, 394 had been previously diagnosed with diabetes mellitus (DM), and the remaining 1465 did not have DM.
The prevalence of neuropathy in patients with and without DM was 77.2% (304 of 394 patients) and 11.7% (172 of 1465 patients), respectively. Patients with diabetic neuropathy were older, had poorer glycemic control, had higher serum creatinine levels, and reported more significant tobacco use than diabetic patients without neuropathy.
Nearly 80% of diabetic patients undergoing foot and ankle surgery at a large academic medical center had diabetic neuropathy. Preoperative recognition of this morbid complication of DM is important to appropriately stratify those diabetic patients into a high-risk category.
这项前瞻性研究的目的是确定接受足踝手术的糖尿病患者中神经病变的患病率。研究假设,与一般糖尿病患者的神经病变历史发生率相比,接受足踝手术的患者中糖尿病神经病变的患病率更高。
在连续42个月的期间内,前瞻性地录入了1859例连续接受足踝手术患者的资料。在这些受试者中,394例先前已被诊断患有糖尿病(DM),其余1465例没有DM。
患有和未患有DM的患者中神经病变的患病率分别为77.2%(394例患者中的304例)和11.7%(1465例患者中的172例)。患有糖尿病神经病变的患者年龄更大,血糖控制更差,血清肌酐水平更高,并且与没有神经病变的糖尿病患者相比,报告的吸烟量更大。
在一家大型学术医疗中心接受足踝手术的糖尿病患者中,近80%患有糖尿病神经病变。术前识别DM的这种病态并发症对于将这些糖尿病患者适当地分层为高危类别很重要。