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危重症患儿的营养治疗。

Nutrition therapy in the critically ill child.

机构信息

Department of Clinical Nutrition, Children's Hospital Colorado, Aurora, Colorado, USA.

出版信息

Curr Opin Crit Care. 2012 Apr;18(2):192-8. doi: 10.1097/MCC.0b013e3283514ba7.

Abstract

PURPOSE OF REVIEW

Malnutrition and obesity are prevalent in children admitted to the pediatric intensive care unit. Nutritional deterioration secondary to suboptimal nutrient delivery can adversely affect outcomes during pediatric critical illness. This review highlights the recent investigations of nutrition assessment, energy balance, indirect calorimetry, nutrition therapy, barriers to nutrient delivery, monitoring during enteral feeding, and the role of nutrition guidelines in critically ill children.

RECENT FINDINGS

Critically ill children are at high risk for energy and protein imbalance. Indirect calorimetry remains the only accurate method to assess energy requirements in this population. Intensive insulin therapy to achieve glycemic control may reduce morbidity and mortality in adults, but risks hypoglycemia in critically ill children. Early enteral nutrition improves nutrition outcomes and adherence to nutrition guidelines can overcome barriers to optimal nutrition therapy.

SUMMARY

Timely and adequate nutrition therapy is essential to improve nutrition outcomes in critically ill children. Further research is required to determine clinical outcome benefits with indirect calorimetry and enteral nutrition guidelines, and to identify optimal glucose targets.

摘要

目的综述

营养不良和肥胖在儿科重症监护病房(PICU)收治的患儿中很常见。由于营养物质输送不足导致的营养恶化可能会对儿科危重病患儿的预后产生不利影响。本综述重点介绍了营养评估、能量平衡、间接测热法、营养治疗、营养物质输送障碍、肠内喂养监测以及营养指南在危重症患儿中的作用等方面的最新研究进展。

最近的发现

危重症患儿存在能量和蛋白质失衡的高风险。间接测热法仍然是评估该人群能量需求的唯一准确方法。强化胰岛素治疗以实现血糖控制可能会降低成人的发病率和死亡率,但在危重症患儿中会增加低血糖的风险。早期肠内营养可改善营养结局,而遵循营养指南可以克服最佳营养治疗的障碍。

总结

及时和充分的营养治疗对于改善危重症患儿的营养结局至关重要。需要进一步研究以确定间接测热法和肠内营养指南的临床结局获益,并确定最佳的血糖目标。

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