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一种用于测试喉内收功能障碍治疗效果的体内犬模型。

An in vivo canine model for testing treatment effects in laryngeal hyperadduction disorders.

作者信息

Green D C, Berke G S

机构信息

UCLA Division of Head and Neck Surgery 90024.

出版信息

Laryngoscope. 1990 Nov;100(11):1229-35. doi: 10.1288/00005537-199011000-00019.

DOI:10.1288/00005537-199011000-00019
PMID:2233089
Abstract

Adductor spastic dysphonia is a voice disorder characterized by a strained, squeezed, effortful voice produced by true and false cord hyperadduction. An in vivo canine model has been developed to simulate hyperadduction of the true cords. Using this model, the thyroarytenoid muscle was found to have a greater effect on intraglottic and subglottic pressure than cricothyroid muscle contraction. The intraglottic and subglottic pressure was reduced after simulated recurrent laryngeal paralysis. This model can be used in future studies to compare laryngeal treatment modalities for disorders that have a component of vocal cord hyperadduction, such as spastic dysphonia.

摘要

内收肌痉挛性发音障碍是一种嗓音障碍,其特征是由真假声带过度内收产生的紧张、挤压、费力的嗓音。已开发出一种活体犬模型来模拟真声带的过度内收。使用该模型发现,甲杓肌对声门内和声门下压力的影响比环甲肌收缩更大。模拟喉返神经麻痹后,声门内和声门下压力降低。该模型可用于未来的研究,以比较针对有声带过度内收成分的疾病(如痉挛性发音障碍)的喉部治疗方式。

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引用本文的文献

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Experiments on Analysing Voice Production: Excised (Human, Animal) and (Animal) Approaches.语音产生分析实验:切除法(人体、动物)及(动物)方法
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