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1
Regenerative capacity of adult cortical thymic epithelial cells.
Proc Natl Acad Sci U S A. 2012 Feb 28;109(9):3463-8. doi: 10.1073/pnas.1118823109. Epub 2012 Feb 13.
2
Generation of both cortical and Aire(+) medullary thymic epithelial compartments from CD205(+) progenitors.
Eur J Immunol. 2013 Mar;43(3):589-94. doi: 10.1002/eji.201243209. Epub 2013 Feb 11.
3
Thymic crosstalk restrains the pool of cortical thymic epithelial cells with progenitor properties.
Eur J Immunol. 2017 Jun;47(6):958-969. doi: 10.1002/eji.201746922. Epub 2017 Apr 13.
4
Checkpoints in the development of thymic cortical epithelial cells.
J Immunol. 2009 Jan 1;182(1):130-7. doi: 10.4049/jimmunol.182.1.130.
5
Qualitative Changes in Cortical Thymic Epithelial Cells Drive Postpartum Thymic Regeneration.
Front Immunol. 2020 Jan 15;10:3118. doi: 10.3389/fimmu.2019.03118. eCollection 2019.
6
Molecular regulatory networks of thymic epithelial cell differentiation.
Differentiation. 2019 May-Jun;107:42-49. doi: 10.1016/j.diff.2019.06.002. Epub 2019 Jun 14.
7
Adult thymic epithelial cell (TEC) progenitors and TEC stem cells: Models and mechanisms for TEC development and maintenance.
Eur J Immunol. 2015 Nov;45(11):2985-93. doi: 10.1002/eji.201545844. Epub 2015 Sep 30.
8
Adult Thymic Medullary Epithelium Is Maintained and Regenerated by Lineage-Restricted Cells Rather Than Bipotent Progenitors.
Cell Rep. 2015 Nov 17;13(7):1432-1443. doi: 10.1016/j.celrep.2015.10.012. Epub 2015 Nov 5.
9
Thymic epithelial progenitor cells and thymus regeneration: an update.
Cell Res. 2007 Jan;17(1):50-5. doi: 10.1038/sj.cr.7310114.

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Paracrine FGF21 dynamically modulates mTOR signaling to regulate thymus function across the lifespan.
Nat Aging. 2025 Apr;5(4):588-606. doi: 10.1038/s43587-024-00801-1. Epub 2025 Feb 19.
2
Consensus prediction of cell type labels in single-cell data with popV.
Nat Genet. 2024 Dec;56(12):2731-2738. doi: 10.1038/s41588-024-01993-3. Epub 2024 Nov 20.
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Neural Crest-Derived Mesenchymal Cells Support Thymic Reconstitution After Lethal Irradiation.
Eur J Immunol. 2025 Jan;55(1):e202451305. doi: 10.1002/eji.202451305. Epub 2024 Nov 16.
4
Generation and repair of thymic epithelial cells.
J Exp Med. 2024 Oct 7;221(10). doi: 10.1084/jem.20230894. Epub 2024 Jul 9.
6
Atypical chemokine receptors in the immune system.
Nat Rev Immunol. 2024 Oct;24(10):753-769. doi: 10.1038/s41577-024-01025-5. Epub 2024 May 7.
7
Tnpo3 controls splicing of the pre-mRNA encoding the canonical TCR α chain of iNKT cells.
Nat Commun. 2023 Jun 20;14(1):3645. doi: 10.1038/s41467-023-39422-4.
10
A Proposed Link Between Acute Thymic Involution and Late Adverse Effects of Chemotherapy.
Front Immunol. 2022 Jul 1;13:933547. doi: 10.3389/fimmu.2022.933547. eCollection 2022.

本文引用的文献

1
Persistent degenerative changes in thymic organ function revealed by an inducible model of organ regrowth.
Aging Cell. 2012 Feb;11(1):169-77. doi: 10.1111/j.1474-9726.2011.00773.x. Epub 2011 Dec 28.
2
Nonrandom attrition of the naive CD8+ T-cell pool with aging governed by T-cell receptor:pMHC interactions.
Proc Natl Acad Sci U S A. 2011 Aug 16;108(33):13694-9. doi: 10.1073/pnas.1107594108. Epub 2011 Aug 3.
3
Three chemokine receptors cooperatively regulate homing of hematopoietic progenitors to the embryonic mouse thymus.
Proc Natl Acad Sci U S A. 2011 May 3;108(18):7517-22. doi: 10.1073/pnas.1016428108. Epub 2011 Apr 18.
4
Thymopoiesis in mice depends on a Foxn1-positive thymic epithelial cell lineage.
Proc Natl Acad Sci U S A. 2010 Sep 21;107(38):16613-8. doi: 10.1073/pnas.1004623107. Epub 2010 Sep 7.
5
Rejuvenation of the aging thymus: growth hormone-mediated and ghrelin-mediated signaling pathways.
Curr Opin Pharmacol. 2010 Aug;10(4):408-24. doi: 10.1016/j.coph.2010.04.015. Epub 2010 Jun 4.
6
Emerging strategies to boost thymic function.
Curr Opin Pharmacol. 2010 Aug;10(4):443-53. doi: 10.1016/j.coph.2010.04.008. Epub 2010 May 4.
7
Thymic involution and immune reconstitution.
Trends Immunol. 2009 Jul;30(7):366-73. doi: 10.1016/j.it.2009.04.003. Epub 2009 Jun 18.
8
Checkpoints in the development of thymic cortical epithelial cells.
J Immunol. 2009 Jan 1;182(1):130-7. doi: 10.4049/jimmunol.182.1.130.
9
An epithelial progenitor pool regulates thymus growth.
J Immunol. 2008 Nov 1;181(9):6101-8. doi: 10.4049/jimmunol.181.9.6101.
10
Delta-like 4 is the essential, nonredundant ligand for Notch1 during thymic T cell lineage commitment.
J Exp Med. 2008 Oct 27;205(11):2515-23. doi: 10.1084/jem.20080829. Epub 2008 Sep 29.

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