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人工流产后即时放置左炔诺孕酮宫内缓释系统的临床观察

[Clinic observation of a levonorgestrel-releasing intrauterine system inserted immediately after artificial abortion].

作者信息

Chen Jing, Wang Xian-jing, Liang Yan, Jin Qin

机构信息

International Peace Maternity & Child Health Hospital, China Welfare Institute, Shanghai, China.

出版信息

Zhonghua Yi Xue Za Zhi. 2011 Dec 6;91(45):3176-8.

Abstract

OBJECTIVE

To compare the contraceptive efficacies and side effects of Mirena (levonorgestrel-releasing intrauterine system, LNG-IUS) inserted immediately after artificial abortion and in the period of regular menstruation.

METHODS

A total of 166 female subjects volunteered for the insertion of LNG-IUS. They were divided into 2 groups. Eighty-six female subjects inserted right after artificial abortion were selected as the observation group and 80 female subjects inserted during the period of regular menstruation as the control group. Follow-up was performed at one year after insertion. Contraceptive efficacies and side effects were compared between two groups.

RESULTS

No pregnancy was found in both groups. No mirena expulsion occurred in neither groups. The continuation rates were 100%and 95%in the observation and control groups respectively (P > 0.05). The rates of abnormal hemorrhage were 27.5% and 36.2% in observation and control groups respectively during the first three months (P < 0.05). And 22.7% and 23.3% subjects suffered amenorrhea respectively in the first year. No significant difference was found in such side effects as amenorrhea, weight gain, acne and swollen breasts between two groups (P > 0.05).

CONCLUSION

Mirena is proved to be an excellent choice for contraception after artificial abortion. Secondary intrauterine surgery may be avoided. And its insertions immediately after artificial abortion or during the period of regular menstruation share the same efficacies.

摘要

目的

比较人工流产后立即放置曼月乐(左炔诺孕酮宫内节育系统,LNG-IUS)与在正常月经期间放置的避孕效果及副作用。

方法

共有166名女性志愿者自愿放置LNG-IUS。她们被分为两组。选择86名人工流产后立即放置的女性作为观察组,80名在正常月经期间放置的女性作为对照组。放置后一年进行随访。比较两组的避孕效果和副作用。

结果

两组均未发现妊娠。两组均未发生曼月乐环脱落。观察组和对照组的续用率分别为100%和95%(P>0.05)。前三个月观察组和对照组的异常出血率分别为27.5%和36.2%(P<0.05)。第一年分别有22.7%和23.3%的受试者出现闭经。两组在闭经、体重增加、痤疮和乳房胀痛等副作用方面无显著差异(P>0.05)。

结论

曼月乐被证明是人工流产后避孕的极佳选择。可避免二次宫内手术。其在人工流产后立即放置或在正常月经期间放置具有相同的效果。

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