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[一项关于警察代谢综合征危险因素的配对病例对照研究]

[A matched case-control study on the risk factors of metabolic syndrome among policemen].

作者信息

Wang Ya-Sha, Yu Zhi-Rui, Yue Song, Liu Qian, Sun Xin, Ma Xiao-Ming, Tian Feng-Shi, Tang Nai-Jun

机构信息

School of Public Health, Tianjin Medical University, China.

出版信息

Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2011 Aug;29(8):567-71.

PMID:22335152
Abstract

OBJECTIVE

To investigate the life style, genetic and occupational risk factors of metabolic syndrome (MS) among policemen.

METHODS

1:4 matched case-control study was used, based on physical examination data of Tianjin Policemen in 2010, 708 patients with MS were randomly selected as cases, which were matched with 2832 healthy controls on the basis of sex and age (+/- 1 year). An epidemiological investigations on the past exposure status of several possible risk factors was conducted, and the data were analyzed with conditional logistic regression.

RESULTS

Fifteen factors related to exposure were identified for MS through univariate conditional logistic regression analysis. Multivariate conditional logistic regression analysis suggested that, seven factors, such as family history of hypertension (OR = 2.406, 95% CI: 1.946-2.975), family history of diabetes (OR = 1.301, 95% CI: 1.043-1.623), smoking (OR = 1.357, 95%CI: 1.010-1.823), snoring (OR = 1.268, 95% CI: 1.043-1.543), work intensity (OR = 4.603, 95% CI: 3.767-5.623), occupational stressful events (OR = 1.524, 95% CI: 1.209-1.922), security policemen (OR = 1.453, 95% CI: 1.127-1.872) and criminal investigation policemen (OR = 2.792, 95% CI: 2.168-3.596), could significantly increase the risk of disease development, but dairy products (OR = 0.782, 95% CI: 0.619-0.989) was a protect factor for MS. The results from population attributable risk factors analysis showed that the control of smoking, snoring, work intensity, occupational stressful events can decreased the risk of MS to 16.26%, 11.71%, 56.87% and 8.97%, respectively.

CONCLUSION

Metabolic syndrome has became a significant public health problem among policemen, it's necessary to take measures on life style, occupational risk factors for reducing the incidence of MS, and improving the health level among policemen.

摘要

目的

探讨警察群体中代谢综合征(MS)的生活方式、遗传和职业危险因素。

方法

采用1:4匹配的病例对照研究,依据2010年天津市警察的体检数据,随机选取708例MS患者作为病例组,按照性别和年龄(±1岁)与2832名健康对照进行匹配。对多种可能危险因素的既往暴露状况进行流行病学调查,并采用条件logistic回归分析数据。

结果

通过单因素条件logistic回归分析确定了15个与MS暴露相关的因素。多因素条件logistic回归分析显示,高血压家族史(OR = 2.406,95%CI:1.946 - 2.975)、糖尿病家族史(OR = 1.301,95%CI:1.043 - 1.623)、吸烟(OR = 1.357,95%CI:1.010 - 1.823)、打鼾(OR = 1.268,95%CI:1.043 - 1.543)、工作强度(OR = 4.603,95%CI:3.767 - 5.623)、职业应激事件(OR = 1.524,95%CI:1.209 - 1.922)、治安警察(OR = 1.453,95%CI:1.127 - 1.872)和刑事侦查警察(OR = 2.792,95%CI:2.168 - 3.596)等7个因素可显著增加发病风险,但乳制品(OR = 0.782,95%CI:0.619 - 0.989)是MS的保护因素。人群归因危险度分析结果表明,控制吸烟、打鼾、工作强度、职业应激事件可使MS发病风险分别降低16.26%、11.71%、56.87%和8.97%。

结论

代谢综合征已成为警察群体中一个重要的公共卫生问题,有必要针对生活方式、职业危险因素采取措施以降低MS的发病率,提高警察群体的健康水平。

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