[农村维吾尔族成年居民慢性牙周炎与高血压的关联]

[The association between chronic periodontitis and hypertension in rural adult Uygur residents].

作者信息

Zhang Li, Li Yu-fang, Liang Zhao-zhong, Ba Peng-fei, Sang Xiao-hong, Liu Jian, Abudula Dilimulati, Wang Wen-li

机构信息

Department of Nephropathy, First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China.

出版信息

Zhonghua Xin Xue Guan Bing Za Zhi. 2011 Dec;39(12):1140-4.

PMID:22336509

Abstract

OBJECTIVE

To explore the association between chronic periodontitis and hypertension in rural adult Uygur residents.

METHODS

A total of 1415 Uygur residents aged 18 and over were selected by random multistage and probability proportional to size from 364 villages in Moyu county of Xinjiang Uygur autonomous region, all subjects received questionnaire, physical examination and biochemical analysis and oral examination. The subjects were categorized as periodontitis group and no periodontitis group, the periodontitis group was further categorized as mild, moderate and severe periodontitis subgroup. The relationship between chronic periodontitis with hypertension was analyzed by Spearman correlation. Binary logistic regression was used to calculate the influential factors for hypertension.

RESULTS

The prevalence rates of chronic periodontitis and hypertension were 66.0% (934/1415) and 33.8% (478/1415), respectively. The prevalence rates of hypertension were 18.7% (90/481), 35.1% (131/373), 32.3% (62/192), 52.8% (195/369) in no periodontitis, mild, moderate and severe periodontitis groups, respectively. Spearman correlation showed an association of chronic periodontitis with hypertension (r(s) = 0.273, P < 0.01). After adjustment for age, gender, body mass index, waist circumference, glycometabolism disorder, hyperlipidemia, chronic kidney disease, multiple logistic regression analysis showed that periodontitis was significantly associated with hypertension (OR = 1.75, 95%CI: 1.30 - 2.36, P < 0.01). Compared with no periodontitis, mild (OR = 1.76, 95%CI: 1.26 - 2.48, P < 0.01) and severe (OR = 2.26, 95%CI: 1.57 - 3.26, P < 0.01) periodontitis were significantly associated with hypertension while moderate periodontitis was not significantly associated with hypertension (OR = 1.21, 95%CI: 0.80 - 1.84, P > 0.05).

CONCLUSION

This study showed an independent association of periodontitis with hypertension in this study cohort.

摘要

目的

探讨新疆维吾尔自治区农村成年维吾尔族居民慢性牙周炎与高血压之间的关联。

方法

采用随机多阶段、按规模大小成比例的抽样方法，从新疆维吾尔自治区墨玉县364个村庄中选取1415名18岁及以上的维吾尔族居民，所有受试者均接受问卷调查、体格检查、生化分析及口腔检查。将受试者分为牙周炎组和非牙周炎组，牙周炎组进一步分为轻度、中度和重度牙周炎亚组。采用Spearman相关性分析慢性牙周炎与高血压之间的关系。采用二元logistic回归分析高血压的影响因素。

结果

慢性牙周炎和高血压的患病率分别为66.0%（934/1415）和33.8%（478/1415）。非牙周炎组、轻度、中度和重度牙周炎组的高血压患病率分别为18.7%（90/481）、35.1%（131/373）、32.3%（62/192）、52.8%（195/369）。Spearman相关性分析显示慢性牙周炎与高血压有关（r(s)=0.273，P<0.01）。在调整年龄、性别、体重指数、腰围、糖代谢紊乱、高脂血症、慢性肾脏病后，多因素logistic回归分析显示牙周炎与高血压显著相关（OR=1.75，95%CI：1.30-2.36，P<0.01）。与非牙周炎相比，轻度（OR=1.76，95%CI：1.26-2.48，P<0.01）和重度（OR=2.（此处原文有误，应为2.2（推测为排版错误）6，95%CI：1.57-3.26，P<0.01）牙周炎与高血压显著相关，而中度牙周炎与高血压无显著相关性（OR=1.21，95%CI：0.80-1.84，P>0.05）。