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急性淋巴细胞白血病患者椎体压缩骨折的经皮椎体成形术

[Percutaneous vertebroplasty for vertebral compression fractures in the patient with acute lymphoblastic leukemia].

作者信息

Nakanishi Shino, Yamamoto Tatsuo, Hiraga Norihito, Abe Yoichiro, Oseto Kiyoshige

机构信息

Department of Anesthesiology, Kumamoto University Hospital, Kumamoto 860-8856.

出版信息

Masui. 2012 Jan;61(1):108-12.

Abstract

Percutaneous vertebroplasty (PVP) is an interventional treatment for painful vertebral compression fractures caused by osteoporosis and malignant diseases such as multiple myeloma and metastatic bone tumors. We present the first case of PVP performed on a man in his thirties with vertebral compression fractures secondary to acute lymphoblastic leukemia. PVP at T11 and L1 levels resulted in a marked improvement in refractory pain although he developed delayed pyogenic spondylitis two months after the intervention. This case suggests that PVP could be one of the useful therapeutic procedures for intractable back pain associated with vertebral compression fractures in acute lymphoblastic leukemia if we are extremely vigilant for the risk of spondylitis.

摘要

经皮椎体成形术(PVP)是一种针对由骨质疏松症以及多发性骨髓瘤和转移性骨肿瘤等恶性疾病引起的疼痛性椎体压缩骨折的介入治疗方法。我们报告了首例对一名三十多岁男性进行的PVP手术,该患者因急性淋巴细胞白血病继发椎体压缩骨折。在T11和L1水平进行的PVP使顽固性疼痛得到了显著改善,尽管他在介入治疗两个月后发生了迟发性化脓性脊柱炎。该病例表明,如果我们对脊柱炎风险保持高度警惕,PVP可能是治疗急性淋巴细胞白血病相关椎体压缩骨折所致顽固性背痛的有效治疗方法之一。

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