Sekiya T, Iwabuchi T, Okabe S, Ishii M
Department of Neurosurgery, Hirosaki University School of Medicine.
No Shinkei Geka. 1990 Oct;18(10):921-6.
Postoperative MR findings of eleven acoustic neuromas were analyzed. MRI's were able to clearly visualize residual tumor around the 7th and 8th cranial nerves that were left to preserve cranial nerve function, although conventional X ray CT scans often failed to detect it due to artifacts in the parapetrous area. The facial nerves preserved during operations were also visualized from their brainstem portion to the internal auditory meatus. These findings indicate that MRI is excellent in delineating soft tissue in the CP angle that would be overlooked by conventional X ray CT scan. It was also found that the nerve bundles within the internal auditory canal gained increased signal intensity on the T1 and proton weighted images after surgical interventions and that this effect extended into the most distal end of the nerve bundles and even into the intracochlear portion of the cochlear nerve. The nerve bundles with increased signal intensity were conspicuously enhanced after intravenous administration of Gd-DTPA. This indicated that the blood nerve barrier of the nerves within the internal auditory canal were disrupted due to the surgical manipulations in excising tumors. Following such surgical manipulations, nerve edema ensued, although manipulations in the cerebello-pontine angle were done carefully and protectively under a surgical microscope. The clinical significance of disruption of the blood nerve barrier and following nerve edema were discussed from the standpoint of preservation of the 7th and 8th cranial nerve functions.
分析了11例听神经瘤的术后磁共振成像(MR)结果。磁共振成像能够清晰显示保留颅神经功能时在第7和第8颅神经周围残留的肿瘤,而传统的X线计算机断层扫描(CT)由于岩骨旁区域的伪影常常无法检测到。术中保留的面神经从脑干部分到内耳道也能清晰显示。这些结果表明,磁共振成像在描绘桥小脑角软组织方面非常出色,而这些软组织会被传统X线CT扫描忽略。还发现,手术干预后,内耳道内的神经束在T1加权像和质子加权像上信号强度增加,且这种效应延伸至神经束的最远端,甚至进入蜗神经的蜗内部分。静脉注射钆喷酸葡胺(Gd-DTPA)后,信号强度增加的神经束明显强化。这表明在内耳道内切除肿瘤的手术操作导致神经血脑屏障被破坏。尽管在手术显微镜下小心且保护性地进行了桥小脑角的操作,但术后仍出现了神经水肿。从保留第7和第8颅神经功能的角度讨论了神经血脑屏障破坏及随后神经水肿的临床意义。