Kumar Suresh, Tiwari Punit, Sharma Pramod, Goel Amit, Singh Jitendra P, Vijay Mukesh K, Gupta Sandeep, Bera Malay K, Kundu Anup K
Department of Urology, IPGME and R, SSKM Hospital, Kolkata, India.
Urol Ann. 2012 Jan;4(1):6-12. doi: 10.4103/0974-7796.91613.
The aim of our study was to evaluate the treatment outcomes of medical and surgical management of urinary tract endometriosis.
Urinary tract endometriosis patients enrolled between Jan 2006 and May 2010 were retrospectively reviewed. Preoperative datas (mode of presentation, diagnosis, imaging), intraoperative findings (location and size of lesion), postoperative histopathology and follow-up were recorded and results were analyzed and the success rate of different modalities of treatment was calculated.
In our study, of nineteen patients, nine had vesical involvement and ten had ureteric involvement. Among the vesical group, the success rate of transurethral resection followed by injection leuproide was 60% (3/5), while among the partial cystectomy group, the success rate was 100%. Among patients with ureteric involvement, success rate of distal ureterectomy and reimplantation was 100%, laparoscopic ureterolysis with Double J stenting followed by injection leuprolide was 75% while that of Gonadotropin- releasing hormone (GnRh) analogue alone was 67%.
One should have a high index of suspicion with irritative voiding symptoms with or without hematuria, with negative urine culture, in all premenopausal women to diagnose urinary tract endometriosis. Partial cystectomy is a better alternative to transurethral resection followed by GnRh analogue in vesical endometriosis. Approach to the ureter must be individualised depending upon the severity of disease and dilatation of the upper tract to maximise the preservation of renal function.
本研究旨在评估尿路子宫内膜异位症的药物及手术治疗效果。
回顾性分析2006年1月至2010年5月收治的尿路子宫内膜异位症患者。记录术前数据(临床表现、诊断、影像学检查)、术中发现(病变位置及大小)、术后组织病理学检查及随访情况,分析结果并计算不同治疗方式的成功率。
本研究中,19例患者中9例累及膀胱,10例累及输尿管。膀胱组中,经尿道电切加注射亮丙瑞林的成功率为60%(3/5),而部分膀胱切除术组的成功率为100%。输尿管受累患者中,远端输尿管切除并再植的成功率为100%,腹腔镜输尿管松解加双J管置入并注射亮丙瑞林的成功率为75%,单纯使用促性腺激素释放激素(GnRh)类似物的成功率为67%。
对于所有有或无血尿的刺激性排尿症状、尿培养阴性的绝经前女性,应高度怀疑尿路子宫内膜异位症。在膀胱子宫内膜异位症中,部分膀胱切除术是比经尿道电切加GnRh类似物更好的选择。输尿管的处理必须根据疾病严重程度和上尿路扩张情况个体化,以最大程度保留肾功能。