Houston S
Division of Infectious Diseases, University of Alberta Hospitals, Edmonton, Alberta.
Can J Infect Dis. 1994 May;5(3):125-9. doi: 10.1155/1994/739818.
Nematodes of the genus Gnathostoma can cause a spectrum of disease in humans. This includes a distinctive syndrome of intermittent migratory subcutaneous swellings, central nervous system involvement with high morbidity and mortality and occasionally, involvement of other organs. Gnathostomiasis is endemic in southern and eastern Asia, particularly Thailand, but has recently been reported from Ecuador and Mexico. Diagnosis is usually based on clinical, epidemiological and serological findings. A recent study suggests that treatment with albendazole is effective. This report describes a patient diagnosed in Canada in whom evidence of pericarditis was associated with gnathostomiasis and in whom treatment with albendazole appears to have been effective.
颚口线虫属的线虫可在人类中引发一系列疾病。这包括一种独特的综合征,即间歇性游走性皮下肿胀、中枢神经系统受累,发病率和死亡率很高,偶尔还会累及其他器官。颚口线虫病在亚洲南部和东部流行,尤其是泰国,但最近在厄瓜多尔和墨西哥也有报道。诊断通常基于临床、流行病学和血清学检查结果。最近的一项研究表明,阿苯达唑治疗有效。本报告描述了一名在加拿大被诊断出患有颚口线虫病且伴有心包炎证据的患者,阿苯达唑治疗似乎对其有效。