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互联网上销售的草药减肥产品使用起来安全吗?

How safe is the use of herbal weight-loss products sold over the internet?

机构信息

Department of Forensic Medicine, Inonu University, Malatya, Turkey.

出版信息

Hum Exp Toxicol. 2013 Jan;32(1):101-6. doi: 10.1177/0960327112436407. Epub 2012 Feb 21.

Abstract

BACKGROUND

In recent years, the use of herbal weight-loss products sold over the Internet has rapidly increased; however, the safety of these products has not been well documented yet. More importantly, the declared ingredients in these products could be different than the marketed contents.

METHODS

Nine different herbal weight-loss products sold over the Internet were obtained. The ingredients of each product were analyzed in the Laboratory of Forensic Medicine and the Scientific and Technological Research Laboratory of Inonu University.

RESULTS

Although all studied weight-loss products were presented as pure herbal, three of them contain sibutramine, three contain caffeine, and three contain caffeine + temazepam. The amount of sibutramine in each capsule was found to be over 10 mg. We analyzed toxic and trace element levels of nine herbal products and found that these herbal products, even in low amounts, contain Pb, Al, Ni, and Ba.

CONCLUSIONS

Our results indicate that herbal weight-loss products available without prescription and claimed to be purely herbal may contain pharmaceutical substances like sibutramine or temazepam in high doses. Moreover, they also may become contaminated with toxic metals. Since people commonly use these products unaware of its real constituents and without the suggestion or control of a physician, they might cause various health problems some of which might be harmful. Strict legal rules and control mechanisms must be established to minimize their possible harmful effects.

摘要

背景

近年来,互联网上销售的草药减肥产品的使用迅速增加;然而,这些产品的安全性尚未得到充分记录。更重要的是,这些产品宣称的成分可能与市场上的成分不同。

方法

从互联网上购买了 9 种不同的草药减肥产品。每种产品的成分均在伊诺努大学法医学实验室和科学技术研究实验室进行了分析。

结果

尽管所有研究的减肥产品都被描述为纯草药,但其中三种含有西布曲明,三种含有咖啡因,三种含有咖啡因+替马西泮。每个胶囊中西布曲明的含量超过 10 毫克。我们分析了 9 种草药产品的有毒和微量元素水平,发现这些草药产品即使含量很低,也含有 Pb、Al、Ni 和 Ba。

结论

我们的结果表明,无需处方即可购买并声称是纯草药的减肥产品可能含有高剂量的西布曲明或替马西泮等药物物质。此外,它们也可能被有毒金属污染。由于人们通常在不知道其真实成分的情况下使用这些产品,也没有医生的建议或控制,因此它们可能会导致各种健康问题,其中一些可能是有害的。必须建立严格的法律规则和控制机制,以尽量减少它们可能产生的有害影响。

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