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[肺气肿和大疱性肺气肿的肺减容手术]

[Lung volume reduction surgery for emphysema and bullous pulmonary emphysema].

作者信息

Le Pimpec-Barthes F, Das Neves-Pereira J-C, Cazes A, Arame A, Grima R, Hubsch J-P, Zukerman C, Hernigou A, Badia A, Bagan P, Delclaux C, Dusser D, Riquet M

机构信息

Service de chirurgie thoracique, hôpital européen Georges-Pompidou, AP-HP, université Paris V-René Descartes, 20 rue Leblanc, Paris cedex 15, France.

出版信息

Rev Pneumol Clin. 2012 Apr;68(2):131-45. doi: 10.1016/j.pneumo.2012.01.010. Epub 2012 Feb 22.

Abstract

The improvement of respiratory symptoms for emphysematous patients by surgery is a concept that has evolved over time. Initially used for giant bullae, this surgery was then applied to patients with diffuse microbullous emphysema. The physiological and pathological concepts underlying these surgical procedures are the same in both cases: improve respiratory performance by reducing the high intrapleural pressure. The functional benefit of lung volume reduction surgery (LVRS) in the severe diffuse emphysema has been validated by the National Emphysema Treatment Trial (NETT) and the later studies which allowed to identify prognostic factors. The quality of the clinical, morphological and functional data made it possible to develop recommendations now widely used in current practice. Surgery for giant bullae occurring on little or moderately emphysematous lung is often a simpler approach but also requires specialised support to optimize its results.

摘要

手术对肺气肿患者呼吸症状的改善是一个随时间演变的概念。该手术最初用于巨大肺大疱,随后应用于弥漫性微肺大疱肺气肿患者。这两种手术的生理和病理概念相同:通过降低高胸膜腔内压来改善呼吸功能。肺减容手术(LVRS)对重度弥漫性肺气肿的功能益处已得到国家肺气肿治疗试验(NETT)及后续研究的验证,这些研究还确定了预后因素。临床、形态学和功能数据的质量使制定目前在当前实践中广泛应用的建议成为可能。发生在轻度或中度肺气肿肺上的巨大肺大疱手术通常是一种更简单的方法,但也需要专业支持以优化其效果。

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