Migliavacca F, Dubini G, de Leval M
Research Assistant, Bioengineering Department, Politecnico di Milano, Milan, Italy.
Images Paediatr Cardiol. 2000 Jan;2(1):11-25.
Computational fluid dynamics techniques have been applied to study both the local and the global haemodynamics created by different surgical reconstructions, currently used to treat complex congenital heart defects. These operations are characterised by competition of flows which can lead to postoperative failure of the surgical treatment. Different techniques have been used in order to improve knowledge of the global haemodynamics in patients submitted to such operations, and to devise possible optimal hydraulic designs of the connections. The adopted approach has combined highly-detailed, three-dimensional models of the connections with simplified zero-dimensional, lumped-parameter network models of the overall circulation of the patient. Three-dimensional models of the connections have been developed by means of the finite element method. Local fluid dynamics features have been analysed and then 'incorporated' in mathematical models able to predict some clinically relevant postoperative haemodynamic data. Results emphasise the impact of local geometry on global haemodynamics.
计算流体动力学技术已被应用于研究不同外科重建所产生的局部和整体血流动力学,这些重建目前用于治疗复杂先天性心脏缺陷。这些手术的特点是血流相互竞争,这可能导致手术治疗的术后失败。为了提高对此类手术患者整体血流动力学的认识,并设计可能的连接最佳水力设计,人们使用了不同的技术。所采用的方法是将连接的高度详细的三维模型与患者整体循环的简化零维集总参数网络模型相结合。连接的三维模型是通过有限元方法开发的。已分析局部流体动力学特征,然后将其“纳入”能够预测一些临床相关术后血流动力学数据的数学模型中。结果强调了局部几何形状对整体血流动力学的影响。