Vaccaro Calogero, Busetto Roberto, Bernardini Daniele, Anselmi Carlo, Zotti Alessandro
Department of Veterinary Clinical Sciences, Radiology Unit, Faculty of Veterinary Medicine, University of Padua, 35020 Legnaro (PD), Italy.
Am J Vet Res. 2012 Mar;73(3):381-4. doi: 10.2460/ajvr.73.3.381.
To evaluate the precision and accuracy of assessing bone mineral density (BMD) by use of mean gray value (MGV) on digitalized and digital images of conventional and digital radiographs, respectively, of ex vivo bovine and equine bone specimens in relation to the gold-standard technique of dual-energy x-ray absorptiometry (DEXA).
Left and right metatarsal bones from 11 beef cattle and right femurs from 2 horses.
Bovine specimens were imaged by use of conventional radiography, whereas equine specimens were imaged by use of computed radiography (digital radiography). Each specimen was subsequently scanned by use of the same DEXA equipment. The BMD values resulting from each DEXA scan were paired with the MGVs obtained by use of software on the corresponding digitalized or digital radiographic image.
The MGV analysis of digitalized and digital x-ray images was a precise (coefficient of variation, 0.1 and 0.09, respectively) and highly accurate method for assessing BMD, compared with DEXA (correlation coefficient, 0.910 and 0.937 for conventional and digital radiography, respectively).
The high correlation between MGV and BMD indicated that MGV analysis may be a reliable alternative to DEXA in assessing radiographic bone density. This may provide a new, inexpensive, and readily available estimate of BMD.
通过分别使用均值灰度值（MGV）来评估体外牛和马骨标本的传统X线片数字化图像及数字X线片上的骨密度（BMD），并与双能X线吸收法（DEXA）的金标准技术进行比较，以评价其精度和准确性。
11头肉牛的左右跖骨和2匹马的右股骨。
牛标本采用传统X线摄影成像，而马标本采用计算机X线摄影（数字X线摄影）成像。随后，每个标本使用同一台DEXA设备进行扫描。每次DEXA扫描得到的BMD值与通过软件在相应数字化或数字X线图像上获得的MGV值配对。
与DEXA相比，数字化和数字X线图像的MGV分析是一种精确的（变异系数分别为0.1和0.09）且高度准确的评估BMD的方法（传统X线摄影和数字X线摄影的相关系数分别为0.910和0.937）。
MGV与BMD之间的高度相关性表明，在评估X线骨密度时，MGV分析可能是DEXA的一种可靠替代方法。这可能提供一种新的、廉价且易于获得的BMD估计方法。
