甲状腺功能亢进猫的肾上腺功能。
Adrenal function in cats with hyperthyroidism.
作者信息
Ramspott Sabine, Hartmann Katrin, Sauter-Louis Carola, Weber Karin, Wehner Astrid
机构信息
Clinic of Small Animal Medicine, LMU University of Munich, Veterinaerstrasse 13, Munich, Germany.
出版信息
J Feline Med Surg. 2012 Apr;14(4):262-6. doi: 10.1177/1098612X11435893. Epub 2012 Jan 16.
Adrenal function may be altered in animals with hyperthyroidism. The aim of the study was to assess adrenal function of hyperthyroid cats (n = 17) compared to healthy cats (n = 18) and cats with chronic diseases (n = 18). Adrenal function was evaluated by adrenocorticotropic hormone (ACTH) stimulation test and the urinary cortisol to creatinine ratio (UCCR) was determined. Length and width of both adrenal glands were measured via ultrasound. Hyperthyroid cats had significantly higher cortisol levels before and after stimulation with ACTH than the other groups. However, the UCCR was not elevated in hyperthyroid cats. The size of the adrenal glands of hyperthyroid cats was not significantly different from the size of those of healthy cats. The results indicate that cats with hyperthyroidism have a higher cortisol secretory capacity in a hospital setting. The normal size of the adrenal glands suggests that cortisol levels may not be increased permanently.
甲状腺功能亢进的动物，其肾上腺功能可能会发生改变。本研究的目的是评估甲状腺功能亢进的猫（n = 17）与健康猫（n = 18）以及患有慢性疾病的猫（n = 18）的肾上腺功能。通过促肾上腺皮质激素（ACTH）刺激试验评估肾上腺功能，并测定尿皮质醇与肌酐比值（UCCR）。通过超声测量双侧肾上腺的长度和宽度。甲状腺功能亢进的猫在ACTH刺激前后的皮质醇水平显著高于其他组。然而，甲状腺功能亢进的猫的UCCR并未升高。甲状腺功能亢进的猫的肾上腺大小与健康猫的肾上腺大小无显著差异。结果表明，在医院环境中，甲状腺功能亢进的猫具有较高的皮质醇分泌能力。肾上腺大小正常表明皮质醇水平可能不会永久性升高。
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