Watson T D, Thompson H
Department of Veterinary Medicine, University of Glasgow Veterinary School.
Vet Rec. 1990 Sep 15;127(11):279-82.
This report describes the clinical and pathological features associated with angiomatous lesions in two calves. In the first case, a single mass located in the atrioventricular ring of the heart was responsible for congestive cardiac failure. The mass was composed of numerous vascular cavities filled with blood and lined by a single layer of well differentiated endothelial cells. The second case had multiple blood-filled cutaneous masses which were confirmed as benign vascular tumours by histological examination of a biopsy specimen. The calf was later euthanased after profuse and uncontrollable haemorrhage from one of the lesions. At necropsy, additional tumours were found in the liver, spleen, kidneys, spinal canal and attached to the pleura, omentum and mesentery. It is proposed that these two cases are representatives of solitary and multiple forms of a syndrome which should be called juvenile bovine angiomatosis.
本报告描述了两只小牛血管瘤病变的临床和病理特征。在第一个病例中，位于心脏房室环的单个肿块导致了充血性心力衰竭。该肿块由许多充满血液的血管腔组成，内衬单层分化良好的内皮细胞。第二个病例有多个充满血液的皮肤肿块，经活检标本组织学检查确认为良性血管肿瘤。这头小牛后来因其中一个病变大量出血且无法控制而被安乐死。尸检时，在肝脏、脾脏、肾脏、椎管以及附着于胸膜、网膜和肠系膜处发现了其他肿瘤。建议将这两个病例作为一种综合征的单发和多发形式的代表，该综合征应称为幼年牛血管瘤病。
