Department of Pediatrics, University of Alberta, Edmonton, Alberta, Canada.
Child Neuropsychol. 2013;19(4):337-49. doi: 10.1080/09297049.2012.658768. Epub 2012 Mar 5.
We examined the pattern of neuropsychological impairments of children with FASD (compared to controls) on NEPSY-II measures of attention and executive functioning, language, memory, visuospatial processing, and social perception.
Participants included 32 children with FASD and 30 typically developing control children, ranging in age from 6 to 16 years. Children were tested on the following subtests of the NEPSY-II: Attention and Executive Functioning (animal sorting, auditory attention/response set, and inhibition), Language (comprehension of instructions and speeded naming), Memory (memory for names/delayed memory for names), Visual-Spatial Processing (arrows), and Social Perception (theory of mind). Groups were compared using MANOVA.
Children with FASD were impaired relative to controls on the following subtests: animal sorting, response set, inhibition (naming and switching conditions), comprehension of instructions, speeded naming, and memory for names total and delayed, but group differences were not significant on auditory attention, inhibition (inhibition condition), arrows, and theory of mind. Among the FASD group, IQ scores were not correlated with performance on the NEPSY-II subtests, and there were no significant differences between those with and without comorbid ADHD.
The NEPSY-II is an effective and useful tool for measuring a variety of neuropsychological impairments among children with FASD. Children with FASD displayed a pattern of results with impairments (relative to controls) on measures of executive functioning (set shifting, concept formation, and inhibition), language, and memory, and relative strengths on measures of basic attention, visual spatial processing, and social perception.
我们研究了 FASD 儿童（与对照组相比）在神经心理测试中的注意力和执行功能、语言、记忆、视空间处理和社会知觉方面的神经心理损伤模式。
参与者包括 32 名 FASD 儿童和 30 名正常发育的对照组儿童，年龄在 6 至 16 岁之间。儿童接受了以下 NEPSY-II 测验的以下分测验：注意力和执行功能（动物分类、听觉注意力/反应设置和抑制）、语言（理解指令和快速命名）、记忆（记忆姓名/延迟记忆姓名）、视觉空间处理（箭头）和社会知觉（心理理论）。使用 MANOVA 对组间进行比较。
与对照组相比，FASD 儿童在以下分测验中表现出损伤：动物分类、反应设置、抑制（命名和切换条件）、理解指令、快速命名以及记忆姓名总数和延迟，但在听觉注意力、抑制（抑制条件）、箭头和心理理论方面，组间差异无统计学意义。在 FASD 组中，智商分数与 NEPSY-II 分测验的表现无关，且伴有和不伴有共患 ADHD 的儿童之间无显著差异。
NEPSY-II 是一种有效且有用的工具，可用于测量 FASD 儿童的各种神经心理损伤。与对照组相比，FASD 儿童在执行功能（转换、概念形成和抑制）、语言和记忆方面的测试结果表现出损伤模式，而在基本注意力、视空间处理和社会知觉方面表现出相对优势。
